Biophysical screening for the discovery of small-molecule ligands

Keyphrases

• Small Molecules 100%
• Chemical Probes 100%
• Biophysical Assays 100%
• Small Molecule Ligands 100%
• Drug Discovery 50%
• Biological Pathways 50%
• Macromolecules 50%
• Pharmaceutical Industry 50%
• Structure-activity Relationship 50%
• Bona Fide 50%
• High-throughput 50%
• Ligand Binding 50%
• Binding Mode 50%
• Isothermal Titration Calorimetry 50%
• Medicinal Chemistry 50%
• Chemical Drugs 50%
• NMR Spectroscopy 50%
• Protein Function 50%
• Target Validation 50%
• Binding Affinity 50%
• Fragment Screening 50%
• Weak Affinity 50%
• Surface Plasmon Resonance 50%
• Biophysical Techniques 50%
• Chemical Biology 50%
• Structure-based Drug Design 50%
• Differential Scanning Fluorimetry 50%
• Fluorescence Method 50%
• Thermal Shift 50%
• Efficient Development 50%
• Ligand-based NMR 50%
• Fluorescence Polarization 50%
• Structural Techniques 50%
• Binding Energetics 50%
• Protein X-ray Crystallography 50%
• Active Chemicals 50%
• Building Structure 50%
• Ligand Screening 50%

Biochemistry, Genetics and Molecular Biology

• Small Molecule 100%
• Energy Transfer 33%
• Macromolecule 33%
• Binding Affinity 33%
• Ligand Binding 33%
• Isothermal Titration Calorimetry 33%
• Protein Function 33%
• Structure Activity Relation 33%
• X-Ray Crystallography 33%
• Surface Plasmon Resonance 33%
• Small-Molecule Screening 33%