Biosensor-Based Approach to the Identification of Protein Kinase Ligands with Dual-Site Modes of Action

Keyphrases

• Mode of Action 100%
• Protein Kinase 100%
• Dual Active Sites 100%
• Binding Site 66%
• T Cells 66%
• Adenosine Triphosphate 66%
• X-ray Crystallography 66%
• Biacore 66%
• Binding Properties 33%
• Catalytic Domain 33%
• High-throughput Screening 33%
• Binding Mode 33%
• Tyrosine Kinase 33%
• Non-competitive 33%
• Surface Plasmon Resonance 33%
• Binder 33%
• Rapid Optimization 33%
• Allosteric Site 33%
• Surface Plasmon Resonance Technology 33%
• Terminal Lobes 33%
• Rapid Identification 33%
• Binding Kinetics 33%

Biochemistry, Genetics and Molecular Biology

• Protein Kinases 100%
• Binding Site 66%
• Adenosine Triphosphate 66%
• Phosphotransferase 66%
• Kinase 66%
• T Cell 66%
• Surface Plasmon Resonance 66%
• Enzyme Active Site 33%
• N-Terminus 33%
• Receptor Tyrosine Kinase 33%
• Tyrosine Kinase 33%
• X Ray 33%
• X-Ray Crystallography 33%
• Binding Kinetics 33%
• Allosteric Site 33%