C-type natriuretic peptide. An endogenous inhibitor of vascular angiotensin-converting enzyme activity

Neil C. Davidson, Craig S. Barr, Allan D. Struthers

    Research output: Contribution to journalArticlepeer-review

    51 Citations (Scopus)

    Abstract

    Atrial and B-type natriuretic peptide are both known to be antagonists of the renin-angiotensin system. C-type natriuretic peptide (CNP) is a new member of this family except that its principal source is the vascular endothelium. This study tested the hypothesis that CNP is a local inhibitor of vascular angiotensin-converting enzyme (ACE) activity.
    Original languageEnglish
    Pages (from-to)1155-1159
    Number of pages5
    JournalCirculation
    Volume93
    Issue number6
    DOIs
    Publication statusPublished - 1996

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