TY - JOUR
T1 - Cadherins, catenins and APC protein
T2 - interplay between cytoskeletal complexes and signaling pathways
AU - Barth, Angela I. M.
AU - Näthke, Inke S.
AU - Nelson, W. James
PY - 1997
Y1 - 1997
N2 - Cadherins play important roles in cell-cell adhesion during tissue differentiation. Cadherins are linked to the actin cytoskeleton by catenins (beta-catenin/armadillo, plakoglobin, and alpha-catenin). Recent results show that beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases and phosphatases and Wnt/Wingless. Interplay between these cytoskeletal complexes and signaling pathways may regulate morphogenesis.
AB - Cadherins play important roles in cell-cell adhesion during tissue differentiation. Cadherins are linked to the actin cytoskeleton by catenins (beta-catenin/armadillo, plakoglobin, and alpha-catenin). Recent results show that beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases and phosphatases and Wnt/Wingless. Interplay between these cytoskeletal complexes and signaling pathways may regulate morphogenesis.
U2 - 10.1016/S0955-0674(97)80122-6
DO - 10.1016/S0955-0674(97)80122-6
M3 - Article
C2 - 9330872
SN - 0955-0674
VL - 9
SP - 683
EP - 690
JO - Current Opinion in Cell Biology
JF - Current Opinion in Cell Biology
IS - 5
ER -