Calculating coherent light-wave propagation in large heterogeneous media

T Vettenburg, S A R Horsley, J Bertolotti

Research output: Contribution to journalArticle

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Abstract

Understanding the interaction of light with a highly scattering material is essential for optical microscopy of optically thick and heterogeneous biological tissues. Ensemble-averaged analytic solutions cannot provide more than general predictions for relatively simple cases. Yet, biological tissues contain chiral organic molecules and many of the cells' structures are birefringent, a property exploited by polarization microscopy for label-free imaging. Solving Maxwell's equations in such materials is a notoriously hard problem. Here we present an efficient method to determine the propagation of electro-magnetic waves in arbitrary anisotropic materials. We demonstrate how the algorithm enables large scale calculations of the scattered light field in complex birefringent materials, chiral media, and even materials with a negative refractive index.

Original languageEnglish
Pages (from-to)11946-11967
Number of pages22
JournalOptics Express
Volume27
Issue number9
DOIs
Publication statusPublished - 29 Apr 2019

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coherent light
wave propagation
microscopy
Maxwell equation
electromagnetic radiation
refractivity
propagation
polarization
predictions
cells
scattering
molecules
interactions

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Vettenburg, T ; Horsley, S A R ; Bertolotti, J. / Calculating coherent light-wave propagation in large heterogeneous media. In: Optics Express. 2019 ; Vol. 27, No. 9. pp. 11946-11967.
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Calculating coherent light-wave propagation in large heterogeneous media. / Vettenburg, T; Horsley, S A R; Bertolotti, J.

In: Optics Express, Vol. 27, No. 9, 29.04.2019, p. 11946-11967.

Research output: Contribution to journalArticle

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