Cancer Biology: APC Delivers Kiss of Death to Focal Adhesions

Inke Näthke (Lead / Corresponding author)

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)
115 Downloads (Pure)

Abstract

New work shows that the actin-nucleating ability of the adenomatous polyposis coli protein is required for disassembly of focal adhesions. Loss of this function in Apc mutant cells reduces directed cell migration, potentially explaining the decreased migration of colon cancer cells.

Original languageEnglish
Pages (from-to)R805-R807
Number of pages3
JournalCurrent Biology
Volume27
Issue number16
Early online date21 Aug 2017
DOIs
Publication statusPublished - 21 Aug 2017

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