Cancer Biology: APC Delivers Kiss of Death to Focal Adhesions

Inke Näthke (Lead / Corresponding author)

    Research output: Contribution to journalArticlepeer-review

    1 Citation (Scopus)
    160 Downloads (Pure)

    Abstract

    New work shows that the actin-nucleating ability of the adenomatous polyposis coli protein is required for disassembly of focal adhesions. Loss of this function in Apc mutant cells reduces directed cell migration, potentially explaining the decreased migration of colon cancer cells.

    Original languageEnglish
    Pages (from-to)R805-R807
    Number of pages3
    JournalCurrent Biology
    Volume27
    Issue number16
    Early online date21 Aug 2017
    DOIs
    Publication statusPublished - 21 Aug 2017

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