Projects per year
Abstract
New work shows that the actin-nucleating ability of the adenomatous polyposis coli protein is required for disassembly of focal adhesions. Loss of this function in Apc mutant cells reduces directed cell migration, potentially explaining the decreased migration of colon cancer cells.
Original language | English |
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Pages (from-to) | R805-R807 |
Number of pages | 3 |
Journal | Current Biology |
Volume | 27 |
Issue number | 16 |
Early online date | 21 Aug 2017 |
DOIs | |
Publication status | Published - 21 Aug 2017 |
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Dive into the research topics of 'Cancer Biology: APC Delivers Kiss of Death to Focal Adhesions'. Together they form a unique fingerprint.Projects
- 2 Finished
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Mechanisms of Intestinal Epithelial Responses to Inflammatory Modulators
Nathke, I. (Investigator) & Swamy, M. (Investigator)
1/12/14 → 31/03/18
Project: Research
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Sonopill: Minimally Invasive Gastrointestinal Diagnosis and Therapy (Joint with University of Glasgow & Heriot Watt University)
Cochran, S. (Investigator), Corner, G. (Investigator), Cuschieri, A. (Investigator), Nathke, I. (Investigator) & Steele, B. (Investigator)
Engineering and Physical Sciences Research Council
27/05/13 → 14/12/18
Project: Research