Abstract
Background: The term "cannabis psychosis" has become ubiquitous in the psychiatric literature. Few authors have described the precise psychopathology of this potentially distinct subtype of psychosis. Specifically, little attention has been paid to exploring whether cannabis psychosis is characterized by a psychopathology which is different from that of other types of psychosis.
Objective: The purpose of this paper was to systematically review the literature for evidence of a specific constellation of symptoms which are consistently characteristic of cannabis psychosis within an inpatient psychiatric setting and to determine whether these combine to create a psychopathology which is distinct from that of other types of psychosis.
Method: Systematic review using Meta-analysis Of Observational Studies in Epidemiology (MOOSE) guidelines.
Results: 13 studies of the 439 identified met the inclusion criteria. Only eight studies had sufficient internal and external validity to allow comparison in a narrative format of the psychopathology present, compared with controls. Of these eight selected studies, seven reported at least one significant difference (p <.05) in the psychopathology of the cannabis group to the control group used as a comparator.
Discussion and Conclusion: This study should be interpreted with great caution and conclusions should not be generalized. These findings do not suggest that "cannabis psychosis" does not exist, only that from a psychopathological perspective it may not be qualitatively any different from other forms of psychosis. Future research in this area needs to focus on clarifying the definition or description of "cannabis psychosis" and the use of standardized robust experimental and/or observational designs to eliminate heterogeneity that may lead to inconclusive results.
| Original language | English |
|---|---|
| Pages (from-to) | S88-S98 |
| Number of pages | 11 |
| Journal | The American Journal on Addictions |
| Volume | 21 |
| Issue number | Suppl 1 |
| DOIs | |
| Publication status | Published - Nov 2012 |
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Cannabis psychosis : examining the evidence for a distinctive psychopathology in a systematic and narrative review. / Baldacchino, Alexander; Hughes, Zoe; Kehoe, Michael; Blair, Hannah; Teh, Ying; Windeatt, Stacey; Crome, Ilana B.
In: The American Journal on Addictions , Vol. 21, No. Suppl 1, 11.2012, p. S88-S98.Research output: Contribution to journal › Article
TY - JOUR
T1 - Cannabis psychosis
T2 - examining the evidence for a distinctive psychopathology in a systematic and narrative review.
AU - Baldacchino, Alexander
AU - Hughes, Zoe
AU - Kehoe, Michael
AU - Blair, Hannah
AU - Teh, Ying
AU - Windeatt, Stacey
AU - Crome, Ilana B.
PY - 2012/11
Y1 - 2012/11
N2 - Background: The term "cannabis psychosis" has become ubiquitous in the psychiatric literature. Few authors have described the precise psychopathology of this potentially distinct subtype of psychosis. Specifically, little attention has been paid to exploring whether cannabis psychosis is characterized by a psychopathology which is different from that of other types of psychosis. Objective: The purpose of this paper was to systematically review the literature for evidence of a specific constellation of symptoms which are consistently characteristic of cannabis psychosis within an inpatient psychiatric setting and to determine whether these combine to create a psychopathology which is distinct from that of other types of psychosis. Method: Systematic review using Meta-analysis Of Observational Studies in Epidemiology (MOOSE) guidelines. Results: 13 studies of the 439 identified met the inclusion criteria. Only eight studies had sufficient internal and external validity to allow comparison in a narrative format of the psychopathology present, compared with controls. Of these eight selected studies, seven reported at least one significant difference (p <.05) in the psychopathology of the cannabis group to the control group used as a comparator. Discussion and Conclusion: This study should be interpreted with great caution and conclusions should not be generalized. These findings do not suggest that "cannabis psychosis" does not exist, only that from a psychopathological perspective it may not be qualitatively any different from other forms of psychosis. Future research in this area needs to focus on clarifying the definition or description of "cannabis psychosis" and the use of standardized robust experimental and/or observational designs to eliminate heterogeneity that may lead to inconclusive results.
AB - Background: The term "cannabis psychosis" has become ubiquitous in the psychiatric literature. Few authors have described the precise psychopathology of this potentially distinct subtype of psychosis. Specifically, little attention has been paid to exploring whether cannabis psychosis is characterized by a psychopathology which is different from that of other types of psychosis. Objective: The purpose of this paper was to systematically review the literature for evidence of a specific constellation of symptoms which are consistently characteristic of cannabis psychosis within an inpatient psychiatric setting and to determine whether these combine to create a psychopathology which is distinct from that of other types of psychosis. Method: Systematic review using Meta-analysis Of Observational Studies in Epidemiology (MOOSE) guidelines. Results: 13 studies of the 439 identified met the inclusion criteria. Only eight studies had sufficient internal and external validity to allow comparison in a narrative format of the psychopathology present, compared with controls. Of these eight selected studies, seven reported at least one significant difference (p <.05) in the psychopathology of the cannabis group to the control group used as a comparator. Discussion and Conclusion: This study should be interpreted with great caution and conclusions should not be generalized. These findings do not suggest that "cannabis psychosis" does not exist, only that from a psychopathological perspective it may not be qualitatively any different from other forms of psychosis. Future research in this area needs to focus on clarifying the definition or description of "cannabis psychosis" and the use of standardized robust experimental and/or observational designs to eliminate heterogeneity that may lead to inconclusive results.
UR - http://www.scopus.com/inward/record.url?scp=84885901900&partnerID=8YFLogxK
U2 - 10.1111/j.1521-0391.2012.00295.x
DO - 10.1111/j.1521-0391.2012.00295.x
M3 - Article
VL - 21
SP - S88-S98
JO - The American Journal on Addictions
JF - The American Journal on Addictions
SN - 1055-0496
IS - Suppl 1
ER -