Projects per year
Abstract
The mRNA cap is a structure that protects mRNA from degradation and recruits processing and translation factors. A new mRNA capping enzyme has been identified, PCIF1/CAPAM, which methylates adenosine when it is the first transcribed nucleotide. This discovery is crucial for understanding the function of cap adenosine methylation.
Original language | English |
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Article number | 1545 |
Pages (from-to) | 183-185 |
Number of pages | 3 |
Journal | Trends in Biochemical Sciences |
Volume | 44 |
Issue number | 3 |
Early online date | 21 Jan 2019 |
DOIs | |
Publication status | Published - 1 Mar 2019 |
Keywords
- CAPAM
- Pcif1
- gene expression
- m6Am
- mRNA cap
- mRNA cap methyltransferase
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Projects
- 2 Active
-
mRNA Cap Regulation and Function in CD8 T Cells (TCAPS)
COMMISSION OF THE EUROPEAN COMMUNITIES
1/05/18 → 31/10/23
Project: Research