Capsule endoscopy: progress update and challenges ahead

Andrea Moglia, Arianna Menciassi, Paolo Dario, Alfred Cuschieri

    Research output: Contribution to journalReview article

    119 Citations (Scopus)

    Abstract

    Capsule endoscopy (CE) enables remote diagnostic inspection of the gastrointestinal tract without sedation and with minimal discomfort. initially intended for small-bowel endoscopy, modifications to the original capsule have since been introduced for imaging of the esophagus and the colon. This review presents a research update on CE. emphasis is placed on PillCam (TM) SB, PillCam (TM) ESO, and PillCam (TM) COLON (Given imaging, Yoqneam, Israel) since the majority of published studies have investigated these devices. Discussion of initial reports on competing devices, such as EndoCapsule (TM) (Olympus, Tokyo, Japan) and MiroCam (TM) (IntroMedic Co., Seoul, republic of Korea) are also included. The last section of this review outlines ongoing research and development directed at the identification of capsule location, control of capsule movement and expansion of the capability of microcameras to enhance the diagnostic power of CE. research efforts aimed at endowing the capsule with a range of functionalities are also discussed, from tissue sampling for biopsy to optical biopsy and, in some cases, actual treatment (interventional CE), so that CE may ultimately replace both diagnostic and interventional flexible endoscopy.

    Original languageEnglish
    Pages (from-to)353-361
    Number of pages9
    JournalNature Reviews Gastroenterology & Hepatology
    Volume6
    Issue number6
    DOIs
    Publication statusPublished - Jun 2009

    Keywords

    • DOUBLE-BALLOON ENTEROSCOPY
    • SMALL-BOWEL TUMORS
    • GASTROESOPHAGEAL-REFLUX DISEASE
    • SINGLE-CENTER EXPERIENCE
    • PILLCAM COLON CAPSULE
    • WIRELESS CAPSULE
    • BARRETTS-ESOPHAGUS
    • CELIAC-DISEASE
    • CROHNS-DISEASE
    • GASTROINTESTINAL-TRACT

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