Captopril: a free radical scavenger

M. Chopra, N. Scott, J. McMurray, J. McLay, A. Bridges, W. E. Smith, J. J. F. Belch

    Research output: Contribution to journalArticle

    97 Citations (Scopus)

    Abstract

    The use of captopril in heart failure and hypertension is becoming increasingly accepted. Captopril has a sulphydryl group in its molecular structure. We wondered if this might confer free radical scavenging activity on the drug and have investigated this in an in vitro system. Results show that captopriol is a free radical scavenger and we suggest that this action might be relevant in its use in heart failure and other vascular and other vascular diseases
    Original languageEnglish
    Pages (from-to)396-399
    Number of pages4
    JournalBritish Journal of Pharmacology
    Volume27
    Issue number3
    DOIs
    Publication statusPublished - 1989

    Fingerprint

    Free Radical Scavengers
    Captopril
    Heart Failure
    Molecular Structure
    Vascular Diseases
    Free Radicals
    Blood Vessels
    Hypertension
    Pharmaceutical Preparations
    In Vitro Techniques

    Cite this

    Chopra, M., Scott, N., McMurray, J., McLay, J., Bridges, A., Smith, W. E., & Belch, J. J. F. (1989). Captopril: a free radical scavenger. British Journal of Pharmacology, 27(3), 396-399. https://doi.org/10.1111/j.1365-2125.1989.tb05384.x
    Chopra, M. ; Scott, N. ; McMurray, J. ; McLay, J. ; Bridges, A. ; Smith, W. E. ; Belch, J. J. F. / Captopril : a free radical scavenger. In: British Journal of Pharmacology. 1989 ; Vol. 27, No. 3. pp. 396-399.
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    author = "M. Chopra and N. Scott and J. McMurray and J. McLay and A. Bridges and Smith, {W. E.} and Belch, {J. J. F.}",
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    Chopra, M, Scott, N, McMurray, J, McLay, J, Bridges, A, Smith, WE & Belch, JJF 1989, 'Captopril: a free radical scavenger', British Journal of Pharmacology, vol. 27, no. 3, pp. 396-399. https://doi.org/10.1111/j.1365-2125.1989.tb05384.x

    Captopril : a free radical scavenger. / Chopra, M.; Scott, N.; McMurray, J.; McLay, J.; Bridges, A.; Smith, W. E.; Belch, J. J. F.

    In: British Journal of Pharmacology, Vol. 27, No. 3, 1989, p. 396-399.

    Research output: Contribution to journalArticle

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    T2 - a free radical scavenger

    AU - Chopra, M.

    AU - Scott, N.

    AU - McMurray, J.

    AU - McLay, J.

    AU - Bridges, A.

    AU - Smith, W. E.

    AU - Belch, J. J. F.

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    DO - 10.1111/j.1365-2125.1989.tb05384.x

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    JF - British Journal of Pharmacology

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    Chopra M, Scott N, McMurray J, McLay J, Bridges A, Smith WE et al. Captopril: a free radical scavenger. British Journal of Pharmacology. 1989;27(3):396-399. https://doi.org/10.1111/j.1365-2125.1989.tb05384.x