Captopril: a free radical scavenger

M. Chopra, N. Scott, J. McMurray, J. McLay, A. Bridges, W. E. Smith, J. J. F. Belch

    Research output: Contribution to journalArticlepeer-review

    98 Citations (Scopus)

    Abstract

    The use of captopril in heart failure and hypertension is becoming increasingly accepted. Captopril has a sulphydryl group in its molecular structure. We wondered if this might confer free radical scavenging activity on the drug and have investigated this in an in vitro system. Results show that captopriol is a free radical scavenger and we suggest that this action might be relevant in its use in heart failure and other vascular and other vascular diseases
    Original languageEnglish
    Pages (from-to)396-399
    Number of pages4
    JournalBritish Journal of Pharmacology
    Volume27
    Issue number3
    DOIs
    Publication statusPublished - 1989

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