Carbamazepine-induced hypersensitivity syndrome occurring in a photodistributed pattern

J. S. Y. So; S. L. Edwards; S. H. Ibbotson

doi:10.1159/000093861

Carbamazepine-induced hypersensitivity syndrome occurring in a photodistributed pattern

J. S. Y. So, S. L. Edwards, S. H. Ibbotson

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

A 76- year- old man was commenced on carbamazepine for partial seizures. This was followed by the development of a rash in an apparently photodistributed pattern, fever, lymphadenopathy, eosinophilia, abnormal liver function tests and atypical lymphocytosis fulfilling the criteria for drug-induced hypersensitivity syndrome. Discontinuation of carbamazepine and application of topical steroid resulted in clearance of the rash, normalization of liver function tests and improvement in eosinophilia. The photodistributed pattern in this case of carbamazepine-induced hypersensitivity syndrome is of interest.

Original language	English
Pages (from-to)	166-168
Number of pages	3
Journal	Dermatology
Volume	213
Issue number	2
DOIs	https://doi.org/10.1159/000093861
Publication status	Published - 2006

Keywords

Epilepsies, Partial
Skin
Diagnosis, Differential
Carbamazepine
Drug Eruptions
Syndrome
Humans
Aged
Follow-Up Studies
Male
Anticonvulsants

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10.1159/000093861

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title = "Carbamazepine-induced hypersensitivity syndrome occurring in a photodistributed pattern",

abstract = "A 76- year- old man was commenced on carbamazepine for partial seizures. This was followed by the development of a rash in an apparently photodistributed pattern, fever, lymphadenopathy, eosinophilia, abnormal liver function tests and atypical lymphocytosis fulfilling the criteria for drug-induced hypersensitivity syndrome. Discontinuation of carbamazepine and application of topical steroid resulted in clearance of the rash, normalization of liver function tests and improvement in eosinophilia. The photodistributed pattern in this case of carbamazepine-induced hypersensitivity syndrome is of interest.",

keywords = "Epilepsies, Partial, Skin, Diagnosis, Differential, Carbamazepine, Drug Eruptions, Syndrome, Humans, Aged, Follow-Up Studies, Male, Anticonvulsants",

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year = "2006",

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AU - So, J. S. Y.

AU - Edwards, S. L.

AU - Ibbotson, S. H.

PY - 2006

Y1 - 2006

N2 - A 76- year- old man was commenced on carbamazepine for partial seizures. This was followed by the development of a rash in an apparently photodistributed pattern, fever, lymphadenopathy, eosinophilia, abnormal liver function tests and atypical lymphocytosis fulfilling the criteria for drug-induced hypersensitivity syndrome. Discontinuation of carbamazepine and application of topical steroid resulted in clearance of the rash, normalization of liver function tests and improvement in eosinophilia. The photodistributed pattern in this case of carbamazepine-induced hypersensitivity syndrome is of interest.

AB - A 76- year- old man was commenced on carbamazepine for partial seizures. This was followed by the development of a rash in an apparently photodistributed pattern, fever, lymphadenopathy, eosinophilia, abnormal liver function tests and atypical lymphocytosis fulfilling the criteria for drug-induced hypersensitivity syndrome. Discontinuation of carbamazepine and application of topical steroid resulted in clearance of the rash, normalization of liver function tests and improvement in eosinophilia. The photodistributed pattern in this case of carbamazepine-induced hypersensitivity syndrome is of interest.

KW - Epilepsies, Partial

KW - Skin

KW - Diagnosis, Differential

KW - Carbamazepine

KW - Drug Eruptions

KW - Syndrome

KW - Humans

KW - Aged

KW - Follow-Up Studies

KW - Male

KW - Anticonvulsants

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DO - 10.1159/000093861

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VL - 213

SP - 166

EP - 168

JO - Dermatology

JF - Dermatology

IS - 2

ER -

Carbamazepine-induced hypersensitivity syndrome occurring in a photodistributed pattern

Abstract

Keywords

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