Cardiac ischemia causes inhibition of the Na/K ATPase by a labile cytosolic compound whose production is linked to oxidant stress

Keyphrases

• Oxidant Stress 100%
• K-ATPase 100%
• Cardiac Ischemia 100%
• Ischemia 40%
• Na+, K+-ATPase Activity 20%
• Intracellular Na 20%
• Room Temperature 10%
• Perfusion 10%
• Skeletal muscle 10%
• Phosphate 10%
• Specific Inhibitor 10%
• Antioxidant 10%
• Ouabain 10%
• Perfused Rat Heart 10%
• Langendorff 10%
• Activity Assay 10%
• Decreased Activity 10%
• Mechanical Recovery 10%
• Bioassay Experiment 10%
• Sarcolemmal Membrane 10%
• Substantial Reduction 10%
• Substrate Availability 10%
• Reperfusion 10%
• Global Ischemia 10%
• Primary Determinants 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Oxidizing Agent 100%
• Adenosine Triphosphatase (Potassium Sodium) 100%
• Heart Muscle Ischemia 100%
• Ischemia 50%
• Adenosine Triphosphatase 20%
• Adenosine Triphosphate 10%
• Antioxidant 10%
• Ouabain 10%

Biochemistry, Genetics and Molecular Biology

• Oxidative Stress 100%
• ATPase 100%
• Homogenate 16%
• Enzyme 8%
• Perfusion 8%
• Skeletal Muscle 8%
• Adenosine Triphosphate 8%
• Room Temperature 8%
• Reperfusion 8%
• Ouabain 8%