Catalytic Friedel-Crafts Alkylation of Electron Rich Aromatic Derivatives with α-Aryl Diazoacetates Mediated by Brønsted Acids

Rafael D. C. Gallo, Patrícia B. Momo, David P. Day, Antonio C. B. Burtoloso (Lead / Corresponding author)

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

The catalytic protonation of aryl diazoacetates by strong Brønsted acids, followed by a Friedel-Crafts alkylation reaction with electron rich aromatic compounds, is reported. The reaction provided in a direct fashion 24 geminal diarylacetates in yields of ≤92%.

Original languageEnglish
Pages (from-to)2239-2343
Number of pages5
JournalACS Applied Materials and Interfaces
Volume22
Issue number6
Early online date5 Mar 2020
DOIs
Publication statusPublished - 20 Mar 2020

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