CDK4/6 inhibitor-mediated cell overgrowth triggers osmotic and replication stress to promote senescence

Lisa Crozier
, Reece Foy
, Rozita Adib
, Ananya Kar
, Jordan A. Holt
, Aanchal U. Pareri
, Juan M. Valverde
, Rene Rivera
, William A. Weston
, Rona Wilson
, Clément Regnault
, Phil Whitfield
, Mihaly Badonyi
, Laura G. Bennett
, Ellen G. Vernon
, Amelia Gamble
, Joseph A. Marsh
, Christopher J. Staples
, Adrian T Saurin
, Alexis R. Barr

Tony Ly (Lead / Corresponding author)

Molecular Cell and Developmental Biology

Research output: Contribution to journal › Article › peer-review

50 Citations (Scopus)

229 Downloads (Pure)

1 Active
2 Finished

3 results

Active
Protein Phosphorylation Dynamics: Investigating A New Dimension Of Regulatory Control
Saurin, A. (Investigator)
1/04/22 → 31/07/26
Project: Research
Finished
Understanding the Proliferation-Quiescence Switch Using Quantitative Cellular Biochemistry (Sir Henry Dale Fellowship) (Transfer from University of Edinburgh)
Ly, T. (Investigator)
1/12/20 → 12/08/24
Project: Research
Kinase-Phosphatase Coupling at the Kinetochore and the Maintenance of Chromosomal Stability (joint with University of Edinburgh)
Saurin, A. (Investigator)
1/06/16 → 30/11/24
Project: Research