TY - GEN
T1 - Cell array fabrication by plasma nanotexturing
AU - Kontziampasis, Dimitrios
AU - Bourkoula, Athanasia
AU - Petrou, Panagiota
AU - Tserepi, Angeliki
AU - Kakabakos, Sotirios
AU - Gogolides, Evangelos
PY - 2013/5/28
Y1 - 2013/5/28
N2 - Cell behavior (i.e. attachment, proliferation, etc.) on nanostructured surfaces is currently a hot topic throughout the scientific community. However, studies often show diverging results due to differences in cells, local surface chemistry, and nanotopography fabrication methods. In this study, we use Oxygen plasma etching to both randomly nanotexture a PMMA surface and change its surface chemistry. We find that 3T3 cells behave quite differently on flat PMMA surfaces as compared to nanotextured ones, showing an on-off attachment behavior. Work is under progress to exploit this effect allowing selective cell capturing, and creation of cell arrays in adjacent plasma-nanotextured/smooth areas using a stencil mask during etching.
AB - Cell behavior (i.e. attachment, proliferation, etc.) on nanostructured surfaces is currently a hot topic throughout the scientific community. However, studies often show diverging results due to differences in cells, local surface chemistry, and nanotopography fabrication methods. In this study, we use Oxygen plasma etching to both randomly nanotexture a PMMA surface and change its surface chemistry. We find that 3T3 cells behave quite differently on flat PMMA surfaces as compared to nanotextured ones, showing an on-off attachment behavior. Work is under progress to exploit this effect allowing selective cell capturing, and creation of cell arrays in adjacent plasma-nanotextured/smooth areas using a stencil mask during etching.
UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84881122465&partnerID=MN8TOARS
U2 - 10.1117/12.2017894
DO - 10.1117/12.2017894
M3 - Conference contribution
T3 - Proceedings of SPIE
BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
A2 - Tserepi, Angeliki
A2 - Delgado-Restituto, Manuel
A2 - Makarona, Eleni
PB - SPIE-International Society for Optical Engineering
T2 - SPIE Microtechnologies 2013
Y2 - 24 April 2013 through 26 April 2013
ER -