Cell array fabrication by plasma nanotexturing

Dimitrios Kontziampasis, Athanasia Bourkoula, Panagiota Petrou, Angeliki Tserepi, Sotirios Kakabakos, Evangelos Gogolides

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Citations (Scopus)


Cell behavior (i.e. attachment, proliferation, etc.) on nanostructured surfaces is currently a hot topic throughout the scientific community. However, studies often show diverging results due to differences in cells, local surface chemistry, and nanotopography fabrication methods. In this study, we use Oxygen plasma etching to both randomly nanotexture a PMMA surface and change its surface chemistry. We find that 3T3 cells behave quite differently on flat PMMA surfaces as compared to nanotextured ones, showing an on-off attachment behavior. Work is under progress to exploit this effect allowing selective cell capturing, and creation of cell arrays in adjacent plasma-nanotextured/smooth areas using a stencil mask during etching.
Original languageEnglish
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
EditorsAngeliki Tserepi, Manuel Delgado-Restituto, Eleni Makarona
PublisherSPIE-International Society for Optical Engineering
Number of pages10
Publication statusPublished - 28 May 2013
EventSPIE Microtechnologies 2013 - Grenoble, France
Duration: 24 Apr 201326 Apr 2013

Publication series

NameProceedings of SPIE


ConferenceSPIE Microtechnologies 2013


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