Cell array fabrication by plasma nanotexturing

Dimitrios Kontziampasis; Athanasia Bourkoula; Panagiota Petrou; Angeliki Tserepi; Sotirios Kakabakos; Evangelos Gogolides

doi:10.1117/12.2017894

Cell array fabrication by plasma nanotexturing

Dimitrios Kontziampasis, Athanasia Bourkoula, Panagiota Petrou, Angeliki Tserepi, Sotirios Kakabakos, Evangelos Gogolides

Mechanical and Electronic Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

5 Citations (Scopus)

Abstract

Cell behavior (i.e. attachment, proliferation, etc.) on nanostructured surfaces is currently a hot topic throughout the scientific community. However, studies often show diverging results due to differences in cells, local surface chemistry, and nanotopography fabrication methods. In this study, we use Oxygen plasma etching to both randomly nanotexture a PMMA surface and change its surface chemistry. We find that 3T3 cells behave quite differently on flat PMMA surfaces as compared to nanotextured ones, showing an on-off attachment behavior. Work is under progress to exploit this effect allowing selective cell capturing, and creation of cell arrays in adjacent plasma-nanotextured/smooth areas using a stencil mask during etching.

Original language	English
Title of host publication	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Editors	Angeliki Tserepi, Manuel Delgado-Restituto, Eleni Makarona
Publisher	SPIE-International Society for Optical Engineering
Number of pages	10
DOIs	https://doi.org/10.1117/12.2017894
Publication status	Published - 28 May 2013
Event	SPIE Microtechnologies 2013 - Grenoble, France Duration: 24 Apr 2013 → 26 Apr 2013

Publication series

Name	Proceedings of SPIE
Volume	8765

Conference

Conference	SPIE Microtechnologies 2013
Country/Territory	France
City	Grenoble
Period	24/04/13 → 26/04/13

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10.1117/12.2017894

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Kontziampasis, D., Bourkoula, A., Petrou, P., Tserepi, A., Kakabakos, S., & Gogolides, E. (2013). Cell array fabrication by plasma nanotexturing. In A. Tserepi, M. Delgado-Restituto, & E. Makarona (Eds.), Progress in Biomedical Optics and Imaging - Proceedings of SPIE [87650B] (Proceedings of SPIE; Vol. 8765). SPIE-International Society for Optical Engineering. https://doi.org/10.1117/12.2017894

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title = "Cell array fabrication by plasma nanotexturing",

abstract = "Cell behavior (i.e. attachment, proliferation, etc.) on nanostructured surfaces is currently a hot topic throughout the scientific community. However, studies often show diverging results due to differences in cells, local surface chemistry, and nanotopography fabrication methods. In this study, we use Oxygen plasma etching to both randomly nanotexture a PMMA surface and change its surface chemistry. We find that 3T3 cells behave quite differently on flat PMMA surfaces as compared to nanotextured ones, showing an on-off attachment behavior. Work is under progress to exploit this effect allowing selective cell capturing, and creation of cell arrays in adjacent plasma-nanotextured/smooth areas using a stencil mask during etching.",

author = "Dimitrios Kontziampasis and Athanasia Bourkoula and Panagiota Petrou and Angeliki Tserepi and Sotirios Kakabakos and Evangelos Gogolides",

year = "2013",

month = may,

day = "28",

doi = "10.1117/12.2017894",

language = "English",

series = "Proceedings of SPIE",

publisher = "SPIE-International Society for Optical Engineering",

editor = "Angeliki Tserepi and Manuel Delgado-Restituto and Eleni Makarona",

booktitle = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

note = "SPIE Microtechnologies 2013 ; Conference date: 24-04-2013 Through 26-04-2013",

}

Kontziampasis, D, Bourkoula, A, Petrou, P, Tserepi, A, Kakabakos, S & Gogolides, E 2013, Cell array fabrication by plasma nanotexturing. in A Tserepi, M Delgado-Restituto & E Makarona (eds), Progress in Biomedical Optics and Imaging - Proceedings of SPIE., 87650B, Proceedings of SPIE, vol. 8765, SPIE-International Society for Optical Engineering, SPIE Microtechnologies 2013, Grenoble, France, 24/04/13. https://doi.org/10.1117/12.2017894

Cell array fabrication by plasma nanotexturing. / Kontziampasis, Dimitrios; Bourkoula, Athanasia; Petrou, Panagiota et al.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. ed. / Angeliki Tserepi; Manuel Delgado-Restituto; Eleni Makarona. SPIE-International Society for Optical Engineering, 2013. 87650B (Proceedings of SPIE; Vol. 8765).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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AB - Cell behavior (i.e. attachment, proliferation, etc.) on nanostructured surfaces is currently a hot topic throughout the scientific community. However, studies often show diverging results due to differences in cells, local surface chemistry, and nanotopography fabrication methods. In this study, we use Oxygen plasma etching to both randomly nanotexture a PMMA surface and change its surface chemistry. We find that 3T3 cells behave quite differently on flat PMMA surfaces as compared to nanotextured ones, showing an on-off attachment behavior. Work is under progress to exploit this effect allowing selective cell capturing, and creation of cell arrays in adjacent plasma-nanotextured/smooth areas using a stencil mask during etching.

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M3 - Conference contribution

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BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

A2 - Tserepi, Angeliki

A2 - Delgado-Restituto, Manuel

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PB - SPIE-International Society for Optical Engineering

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Cell array fabrication by plasma nanotexturing

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