Cellular depletion of atypical PKC lambda is associated with enhanced insulin sensitivity and glucose uptake in L6 rat skeletal muscle cells

Keyphrases

• Insulin Sensitivity 100%
• Rat Skeletal muscle 100%
• Glucose Uptake 100%
• Skeletal muscle Cells 100%
• Atypical PKC 100%
• Lambda 100%
• Insulin 57%
• Protein Kinase B 57%
• Insulin Receptor Substrate 1 (IRS1) 57%
• RNA Interference 28%
• Phosphoinositide 3-kinase (PI3K) 28%
• Insulin Signaling 28%
• Glucose Transport 28%
• Glucose-stimulated Insulin Secretion 28%
• Muscle Cells 28%
• PKCζ 28%
• Overexpression 14%
• Skeletal muscle 14%
• Phosphorylation 14%
• Glycogen Synthase Kinase 3 (GSK3) 14%
• Protein Expression 14%
• Downstream Targets 14%
• Protein Kinase C Isoforms 14%
• Lipids 14%
• Phosphate 14%
• Tensin Homolog 14%
• Glucose Transporter 4 (GLUT4) 14%
• Glucose Transporter 1 (GLUT1) 14%
• Wortmannin 14%
• Insulin Receptor 14%
• Insulin Action 14%
• Ceramide 14%
• Chromosome 10 14%
• Phosphatidylinositol 3-kinase Inhibitor 14%
• Protein Kinase B/Akt 14%
• Negatively Regulate 14%
• Dominant-negative mutant 14%
• Insulin Sensitizers 14%
• AS160 14%
• Signaling Events 14%
• L6 Skeletal muscle Cells 14%
• APKC 14%
• L6 muscle Cells 14%
• Basal State 14%
• Insulin Signaling Molecule 14%

Medicine and Dentistry

• Glucose Uptake 100%
• Skeletal Muscle Cell 100%
• Insulin Sensitivity 100%
• Protein Kinase B 83%
• Insulin Signaling 50%
• Insulin Receptor Substrate 1 50%
• Protein Kinase B 50%
• Phosphoinositide 3-Kinase 33%
• Adipose Tissue 16%
• Glycogen Synthase Kinase 3 16%
• Glucose Transporter 4 16%
• Wortmannin 16%
• Phosphoinositide 3-Kinase Inhibitor 16%
• Protein Kinase C 16%
• Signaling Molecule 16%
• Insulin Receptor Substrate 16%
• RNA Interference 16%
• Ceramide 16%
• Tensin 16%
• Insulin Receptor 16%
• Glucose Transporter 1 16%
• Chromosome 10 16%
• Skeletal Muscle 16%
• RNAI 16%

Biochemistry, Genetics and Molecular Biology

• Skeletal Muscle 100%
• Glucose Transport 100%
• Insulin Sensitivity 100%
• Protein Kinase B 83%
• Insulin Receptor 66%
• Insulin Signaling 50%
• Protein Kinase B 50%
• Phosphoinositide 3-Kinase 33%
• Cyclic Adenosine Monophosphate 16%
• RNA Interference 16%
• Glycogen Synthase Kinase 3 16%
• Isoform 16%
• Phosphoinositide 3-Kinase Inhibitor 16%
• Protein Kinase C 16%
• Lipid 16%
• Tensin 16%
• GLUT4 16%
• Chromosome 10 16%
• RNAI 16%
• Glucose Transporter 16%
• Ceramide 16%