Challenges of treating asthma in people who smoke

Mark Spears; Euan Cameron; Rekha Chaudhuri; Neil C. Thomson

doi:10.1586/eci.09.85

Challenges of treating asthma in people who smoke

Mark Spears (Lead / Corresponding author), Euan Cameron, Rekha Chaudhuri, Neil C. Thomson

Research output: Contribution to journal › Review article › peer-review

24 Citations (Scopus)

Abstract

Cigarette smoking is common in asthma and is associated with poor symptom control and a reduced therapeutic response to inhaled and oral corticosteroids as compared with nonsmokers with asthma. This review examines the range of adverse health effects of smoking in asthma, the inflammatory mechanisms that may influence the efficacy of current drugs and discusses potential future therapeutic directions.

Original language	English
Pages (from-to)	257-268
Number of pages	12
Journal	Expert Review of Clinical Immunology
Volume	6
Issue number	2
DOIs	https://doi.org/10.1586/eci.09.85
Publication status	Published - Mar 2010

Keywords

Airway inflammation
Asthma
Combination therapy
Corticosteroid
Corticosteroid insensitivity
Leukotriene-receptor antagonist
Smoker
Smoking cessation
Theophylline

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1586/eci.09.85

Cite this

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abstract = "Cigarette smoking is common in asthma and is associated with poor symptom control and a reduced therapeutic response to inhaled and oral corticosteroids as compared with nonsmokers with asthma. This review examines the range of adverse health effects of smoking in asthma, the inflammatory mechanisms that may influence the efficacy of current drugs and discusses potential future therapeutic directions.",

keywords = "Airway inflammation, Asthma, Combination therapy, Corticosteroid, Corticosteroid insensitivity, Leukotriene-receptor antagonist, Smoker, Smoking cessation, Theophylline",

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AB - Cigarette smoking is common in asthma and is associated with poor symptom control and a reduced therapeutic response to inhaled and oral corticosteroids as compared with nonsmokers with asthma. This review examines the range of adverse health effects of smoking in asthma, the inflammatory mechanisms that may influence the efficacy of current drugs and discusses potential future therapeutic directions.

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KW - Asthma

KW - Combination therapy

KW - Corticosteroid

KW - Corticosteroid insensitivity

KW - Leukotriene-receptor antagonist

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KW - Smoking cessation

KW - Theophylline

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Challenges of treating asthma in people who smoke

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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