Characteristics of 5-aminolaevulinic acid-induced protoporphyrin IX fluorescence in human skin in vivo

S. H. Ibbotson; C. Jong; A. Lesar; J. S. Ferguson; M. Padgett; M. O'Dwyer; R. Barnetson; J. Ferguson

doi:10.1111/j.1600-0781.2006.00202.x

Characteristics of 5-aminolaevulinic acid-induced protoporphyrin IX fluorescence in human skin in vivo

S. H. Ibbotson, C. Jong, A. Lesar, J. S. Ferguson, M. Padgett, M. O'Dwyer, R. Barnetson, J. Ferguson

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

Topical photodynamic therapy (PDT) is increasingly being used to treat skin cancers. Knowledge of the detailed characteristics of 5-aminolaevulinic acid (ALA)-induced protoporphyrin IX (PpIX) fluorescence in diseased and normal skin is incomplete. Understanding the characteristics of PpIX fluorescence in normal skin may facilitate optimization of PDT regimes while minimizing side effects in the surrounding normal skin. We investigated the characteristics of ALA-induced PpIX fluorescence in normal skin.

Original language	English
Pages (from-to)	105-110
Number of pages	6
Journal	Photodermatology, Photoimmunology & Photomedicine
Volume	22
Issue number	2
DOIs	https://doi.org/10.1111/j.1600-0781.2006.00202.x
Publication status	Published - 2006

Keywords

Reference Values
Skin
Fluorescence
Humans
Adult
Middle Aged
Protoporphyrins
Male
Female
Aminolevulinic Acid

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1600-0781.2006.00202.x

Cite this

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title = "Characteristics of 5-aminolaevulinic acid-induced protoporphyrin IX fluorescence in human skin in vivo",

abstract = "Topical photodynamic therapy (PDT) is increasingly being used to treat skin cancers. Knowledge of the detailed characteristics of 5-aminolaevulinic acid (ALA)-induced protoporphyrin IX (PpIX) fluorescence in diseased and normal skin is incomplete. Understanding the characteristics of PpIX fluorescence in normal skin may facilitate optimization of PDT regimes while minimizing side effects in the surrounding normal skin. We investigated the characteristics of ALA-induced PpIX fluorescence in normal skin.",

keywords = "Reference Values, Skin, Fluorescence, Humans, Adult, Middle Aged, Protoporphyrins, Male, Female, Aminolevulinic Acid",

author = "Ibbotson, {S. H.} and C. Jong and A. Lesar and Ferguson, {J. S.} and M. Padgett and M. O'Dwyer and R. Barnetson and J. Ferguson",

year = "2006",

doi = "10.1111/j.1600-0781.2006.00202.x",

language = "English",

volume = "22",

pages = "105--110",

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T1 - Characteristics of 5-aminolaevulinic acid-induced protoporphyrin IX fluorescence in human skin in vivo

AU - Ibbotson, S. H.

AU - Jong, C.

AU - Lesar, A.

AU - Ferguson, J. S.

AU - Padgett, M.

AU - O'Dwyer, M.

AU - Barnetson, R.

AU - Ferguson, J.

PY - 2006

Y1 - 2006

N2 - Topical photodynamic therapy (PDT) is increasingly being used to treat skin cancers. Knowledge of the detailed characteristics of 5-aminolaevulinic acid (ALA)-induced protoporphyrin IX (PpIX) fluorescence in diseased and normal skin is incomplete. Understanding the characteristics of PpIX fluorescence in normal skin may facilitate optimization of PDT regimes while minimizing side effects in the surrounding normal skin. We investigated the characteristics of ALA-induced PpIX fluorescence in normal skin.

AB - Topical photodynamic therapy (PDT) is increasingly being used to treat skin cancers. Knowledge of the detailed characteristics of 5-aminolaevulinic acid (ALA)-induced protoporphyrin IX (PpIX) fluorescence in diseased and normal skin is incomplete. Understanding the characteristics of PpIX fluorescence in normal skin may facilitate optimization of PDT regimes while minimizing side effects in the surrounding normal skin. We investigated the characteristics of ALA-induced PpIX fluorescence in normal skin.

KW - Reference Values

KW - Skin

KW - Fluorescence

KW - Humans

KW - Adult

KW - Middle Aged

KW - Protoporphyrins

KW - Male

KW - Female

KW - Aminolevulinic Acid

U2 - 10.1111/j.1600-0781.2006.00202.x

DO - 10.1111/j.1600-0781.2006.00202.x

M3 - Article

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SN - 0905-4383

VL - 22

SP - 105

EP - 110

JO - Photodermatology, Photoimmunology & Photomedicine

JF - Photodermatology, Photoimmunology & Photomedicine

IS - 2

ER -

Characteristics of 5-aminolaevulinic acid-induced protoporphyrin IX fluorescence in human skin in vivo

Abstract

Keywords

UN SDGs

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