Activities per year
Abstract
Understanding, and accurately being able to predict, breast cancer risk would greatly enhance the early detection, and hence treatment, of the disease. In this paper we describe a new metric for mammographic structure, "orientated mammographic entropy", via a comprehensive classification of image pixels into one of seven basic image feature (BIF) classes. These classes are flat (zero order), slope-like (first order), and maximum, minimum, light-lines, dark-lines and saddles (second order). By computing a reference breast orientation with respect to breast shape and nipple location, these classes are further subdivided into 23 orientated BIF classes. For a given mammogram a histogram is constructed from the proportion of pixels in each of the 23 classes, and the orientated mammographic entropy, H , computed from this histogram. H , shows good correlation between left and right breasts (r =0.76, N=478), and is independent of both mammographic breast area, a surrogate for breast size (r =0.07, N=974), and breast density, as estimated using Volpara software (r =0.11, N=385). We illustrate this metric by examining its relationship to familial breast cancer risk, for 118 subjects, using the BOADICEA genetic susceptibility to breast and ovarian cancer model.
Original language | English |
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Title of host publication | Breast Imaging |
Subtitle of host publication | 11th International Workshop, IWDM 2012, Philadelphia, PA, USA, July 8-11, 2012. Proceedings |
Editors | Andrew D. A. Maidment, Predrag R. Bakic, Sara Gavenonis |
Place of Publication | Berlin |
Publisher | Springer |
Pages | 181-188 |
Number of pages | 8 |
ISBN (Electronic) | 9783642312717 |
ISBN (Print) | 9783642312700 |
DOIs | |
Publication status | Published - 2012 |
Event | 11th International Workshop on Breast Imaging - Houston Hall, University of Pennsylvania , Philadelphia, United States Duration: 8 Jul 2012 → 11 Jul 2012 http://www.iwdm2012.org/tiki-index.php |
Publication series
Name | Lecture notes in computer science |
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Publisher | Springer |
Volume | 7361 |
Workshop
Workshop | 11th International Workshop on Breast Imaging |
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Abbreviated title | IWDM 2012 |
Country/Territory | United States |
City | Philadelphia |
Period | 8/07/12 → 11/07/12 |
Internet address |
Fingerprint
Dive into the research topics of 'Characterizing breast phenotype with a novel measure of fibroglandular structure'. Together they form a unique fingerprint.Activities
- 4 Participation in workshop, seminar, course
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11th International Workshop on Breast Imaging
Vinnicombe, S. J. (Participant)
9 Jul 2012Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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11th International Workshop on Breast Imaging
Evans, A. (Participant)
9 Jul 2012Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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11th International Workshop on Breast Imaging
Berg, J. (Participant)
9 Jul 2012Activity: Participating in or organising an event types › Participation in workshop, seminar, course