Chemoenzymatic synthesis of sialooligosaccharides on arrays for studies of cell surface adhesion

Robert Sardzik, Ritu Sharma, Sara Kaloo, Josef Voglmeir, Paul R. Crocker, Sabine L. Flitsch

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    30 Citations (Scopus)

    Abstract

    Sialooligosaccharides were generated by direct enzymatic glycosylation on arrays and the resulting surfaces were suitable for the study of carbohydrate-specific cell adhesion.

    Original languageEnglish
    Pages (from-to)5425-5427
    Number of pages3
    JournalChemical Communications
    Volume47
    Issue number19
    DOIs
    Publication statusPublished - 2011

    Keywords

    • Self-assembled monolayers
    • Cruzi-trans-sialidase
    • Mass spectrometry
    • Enzymatic glycosylation
    • Protein interactions
    • Peptide arrays
    • Gold
    • Microarray
    • Binding
    • Tools

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