Choroid plexus and CSF: an updated review

Dana Hutton; Mohammed Gadoora Fadelalla; Avinash Kumar Kanodia; Kismet Hossain-Ibrahim

doi:10.1080/02688697.2021.1903390

Choroid plexus and CSF: an updated review

Dana Hutton, Mohammed Gadoora Fadelalla, Avinash Kumar Kanodia (Lead / Corresponding author), Kismet Hossain-Ibrahim

Research output: Contribution to journal › Review article › peer-review

16 Citations (Scopus)

Abstract

In this article, we review the available literature about the functions of the choroid plexus (ChP), including its basic role in cerebrospinal fluid (CSF) secretion, renewal and absorption. We discuss more recently described, lesser-known functions of the ChP, such as its role in circadian rhythm regulation, chemical and immune surveillance and functional implications of ChP disruption, as occurs in neurodegenerative disorders.

Original language	English
Pages (from-to)	307-315
Number of pages	9
Journal	British Journal of Neurosurgery
Volume	36
Issue number	3
Early online date	6 Apr 2021
DOIs	https://doi.org/10.1080/02688697.2021.1903390
Publication status	Published - 4 May 2022

Keywords

Alzheimer’s disease
Choroid plexus
blood-cerebrospinal fluid barrier
brain disorders
cerebrospinal fluid
chemical surveillance
circadian clock
immune surveillance
normal pressure hydrocephalus
taste and olfactory signalling

ASJC Scopus subject areas

Surgery
Clinical Neurology

Access to Document

10.1080/02688697.2021.1903390

Cite this

@article{0646b77c2e3c4dd782aeb14cf941db1c,

title = "Choroid plexus and CSF: an updated review",

abstract = "In this article, we review the available literature about the functions of the choroid plexus (ChP), including its basic role in cerebrospinal fluid (CSF) secretion, renewal and absorption. We discuss more recently described, lesser-known functions of the ChP, such as its role in circadian rhythm regulation, chemical and immune surveillance and functional implications of ChP disruption, as occurs in neurodegenerative disorders.",

keywords = "Alzheimer{\textquoteright}s disease, Choroid plexus, blood-cerebrospinal fluid barrier, brain disorders, cerebrospinal fluid, chemical surveillance, circadian clock, immune surveillance, normal pressure hydrocephalus, taste and olfactory signalling",

author = "Dana Hutton and Fadelalla, {Mohammed Gadoora} and Kanodia, {Avinash Kumar} and Kismet Hossain-Ibrahim",

note = "Publisher Copyright: {\textcopyright} 2021 The Neurosurgical Foundation.",

year = "2022",

month = may,

day = "4",

doi = "10.1080/02688697.2021.1903390",

language = "English",

volume = "36",

pages = "307--315",

journal = "British Journal of Neurosurgery",

issn = "0268-8697",

publisher = "Informa Healthcare",

number = "3",

}

TY - JOUR

T1 - Choroid plexus and CSF

T2 - an updated review

AU - Hutton, Dana

AU - Fadelalla, Mohammed Gadoora

AU - Kanodia, Avinash Kumar

AU - Hossain-Ibrahim, Kismet

PY - 2022/5/4

Y1 - 2022/5/4

N2 - In this article, we review the available literature about the functions of the choroid plexus (ChP), including its basic role in cerebrospinal fluid (CSF) secretion, renewal and absorption. We discuss more recently described, lesser-known functions of the ChP, such as its role in circadian rhythm regulation, chemical and immune surveillance and functional implications of ChP disruption, as occurs in neurodegenerative disorders.

AB - In this article, we review the available literature about the functions of the choroid plexus (ChP), including its basic role in cerebrospinal fluid (CSF) secretion, renewal and absorption. We discuss more recently described, lesser-known functions of the ChP, such as its role in circadian rhythm regulation, chemical and immune surveillance and functional implications of ChP disruption, as occurs in neurodegenerative disorders.

KW - Alzheimer’s disease

KW - Choroid plexus

KW - blood-cerebrospinal fluid barrier

KW - brain disorders

KW - cerebrospinal fluid

KW - chemical surveillance

KW - circadian clock

KW - immune surveillance

KW - normal pressure hydrocephalus

KW - taste and olfactory signalling

UR - http://www.scopus.com/inward/record.url?scp=85103913713&partnerID=8YFLogxK

U2 - 10.1080/02688697.2021.1903390

DO - 10.1080/02688697.2021.1903390

M3 - Review article

C2 - 33821737

SN - 0268-8697

VL - 36

SP - 307

EP - 315

JO - British Journal of Neurosurgery

JF - British Journal of Neurosurgery

IS - 3

ER -

Choroid plexus and CSF: an updated review

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this