Choroid plexus and CSF: an updated review

Dana Hutton, Mohammed Gadoora Fadelalla, Avinash Kumar Kanodia (Lead / Corresponding author), Kismet Hossain-Ibrahim

    Research output: Contribution to journalReview articlepeer-review

    Abstract

    In this article, we review the available literature about the functions of the choroid plexus (ChP), including its basic role in cerebrospinal fluid (CSF) secretion, renewal and absorption. We discuss more recently described, lesser-known functions of the ChP, such as its role in circadian rhythm regulation, chemical and immune surveillance and functional implications of ChP disruption, as occurs in neurodegenerative disorders.

    Original languageEnglish
    Number of pages9
    JournalBritish Journal of Neurosurgery
    Early online date6 Apr 2021
    DOIs
    Publication statusE-pub ahead of print - 6 Apr 2021

    Keywords

    • Alzheimer’s disease
    • Choroid plexus
    • blood-cerebrospinal fluid barrier
    • brain disorders
    • cerebrospinal fluid
    • chemical surveillance
    • circadian clock
    • immune surveillance
    • normal pressure hydrocephalus
    • taste and olfactory signalling

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