Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P3) and lack a PtdIns(3,4,5)P3 response to cytokines and chemotactic factors; effects reversed by imatinib [9]

H. G. Hamzah; A. Pierce; W. A. Stewart; C. Peter  Downes; A. Gray; A. Irvine; E. Spooncer; A. D. Whetton

doi:10.1038/sj.leu.2403919

Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P₃) and lack a PtdIns(3,4,5)P₃ response to cytokines and chemotactic factors; effects reversed by imatinib [9]

H. G. Hamzah, A. Pierce, W. A. Stewart, C. Peter Downes, A. Gray, A. Irvine, E. Spooncer, A. D. Whetton

Biological Chemistry and Drug Discovery

Research output: Contribution to journal › Letter › peer-review

3 Citations (Scopus)

Original language	English
Pages (from-to)	1851-1853
Number of pages	3
Journal	Leukemia
Volume	19
Issue number	10
DOIs	https://doi.org/10.1038/sj.leu.2403919
Publication status	Published - 18 Aug 2005

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10.1038/sj.leu.2403919

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Hamzah, H. G., Pierce, A., Stewart, W. A., Downes, C. P., Gray, A., Irvine, A., Spooncer, E., & Whetton, A. D. (2005). Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P₃) and lack a PtdIns(3,4,5)P₃ response to cytokines and chemotactic factors; effects reversed by imatinib [9]. Leukemia, 19(10), 1851-1853. https://doi.org/10.1038/sj.leu.2403919

Hamzah, H. G. ; Pierce, A. ; Stewart, W. A. ; Downes, C. Peter ; Gray, A. ; Irvine, A. ; Spooncer, E. ; Whetton, A. D. / Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P₃) and lack a PtdIns(3,4,5)P₃ response to cytokines and chemotactic factors; effects reversed by imatinib [9]. In: Leukemia. 2005 ; Vol. 19, No. 10. pp. 1851-1853.

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title = "Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P3) and lack a PtdIns(3,4,5)P3 response to cytokines and chemotactic factors; effects reversed by imatinib [9]",

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Hamzah, HG, Pierce, A, Stewart, WA, Downes, CP , Gray, A, Irvine, A, Spooncer, E & Whetton, AD 2005, 'Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P₃) and lack a PtdIns(3,4,5)P₃ response to cytokines and chemotactic factors; effects reversed by imatinib [9]', Leukemia, vol. 19, no. 10, pp. 1851-1853. https://doi.org/10.1038/sj.leu.2403919

Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P₃) and lack a PtdIns(3,4,5)P₃ response to cytokines and chemotactic factors; effects reversed by imatinib [9]. / Hamzah, H. G.; Pierce, A.; Stewart, W. A.; Downes, C. Peter ; Gray, A.; Irvine, A.; Spooncer, E.; Whetton, A. D.

In: Leukemia, Vol. 19, No. 10, 18.08.2005, p. 1851-1853.

Research output: Contribution to journal › Letter › peer-review

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AU - Pierce, A.

AU - Stewart, W. A.

AU - Downes, C. Peter

AU - Gray, A.

AU - Irvine, A.

AU - Spooncer, E.

AU - Whetton, A. D.

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SP - 1851

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JO - Leukemia

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Hamzah HG, Pierce A, Stewart WA, Downes CP , Gray A, Irvine A et al. Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P₃) and lack a PtdIns(3,4,5)P₃ response to cytokines and chemotactic factors; effects reversed by imatinib [9]. Leukemia. 2005 Aug 18;19(10):1851-1853. https://doi.org/10.1038/sj.leu.2403919