Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P3) and lack a PtdIns(3,4,5)P3 response to cytokines and chemotactic factors; effects reversed by imatinib [9]

H. G. Hamzah; A. Pierce; W. A. Stewart; C. Peter  Downes; A. Gray; A. Irvine; E. Spooncer; A. D. Whetton

doi:10.1038/sj.leu.2403919

Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P₃) and lack a PtdIns(3,4,5)P₃ response to cytokines and chemotactic factors; effects reversed by imatinib [9]

H. G. Hamzah, A. Pierce, W. A. Stewart, C. Peter Downes, A. Gray, A. Irvine, E. Spooncer, A. D. Whetton

Biological Chemistry and Drug Discovery

Research output: Contribution to journal › Letter › peer-review

5 Citations (Scopus)

Original language	English
Pages (from-to)	1851-1853
Number of pages	3
Journal	Leukemia
Volume	19
Issue number	10
DOIs	https://doi.org/10.1038/sj.leu.2403919
Publication status	Published - 18 Aug 2005

ASJC Scopus subject areas

Hematology
Cancer Research
Anesthesiology and Pain Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/sj.leu.2403919

Cite this

Hamzah, H. G., Pierce, A., Stewart, W. A., Downes, C. P., Gray, A., Irvine, A., Spooncer, E., & Whetton, A. D. (2005). Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P₃) and lack a PtdIns(3,4,5)P₃ response to cytokines and chemotactic factors; effects reversed by imatinib [9]. Leukemia, 19(10), 1851-1853. https://doi.org/10.1038/sj.leu.2403919

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title = "Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P3) and lack a PtdIns(3,4,5)P3 response to cytokines and chemotactic factors; effects reversed by imatinib [9]",

author = "Hamzah, {H. G.} and A. Pierce and Stewart, {W. A.} and Downes, {C. Peter} and A. Gray and A. Irvine and E. Spooncer and Whetton, {A. D.}",

year = "2005",

month = aug,

day = "18",

doi = "10.1038/sj.leu.2403919",

language = "English",

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pages = "1851--1853",

journal = "Leukemia",

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Hamzah, HG, Pierce, A, Stewart, WA, Downes, CP , Gray, A, Irvine, A, Spooncer, E & Whetton, AD 2005, 'Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P₃) and lack a PtdIns(3,4,5)P₃ response to cytokines and chemotactic factors; effects reversed by imatinib [9]', Leukemia, vol. 19, no. 10, pp. 1851-1853. https://doi.org/10.1038/sj.leu.2403919

Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P₃) and lack a PtdIns(3,4,5)P₃ response to cytokines and chemotactic factors; effects reversed by imatinib [9]. / Hamzah, H. G.; Pierce, A.; Stewart, W. A. et al.
In: Leukemia, Vol. 19, No. 10, 18.08.2005, p. 1851-1853.

Research output: Contribution to journal › Letter › peer-review

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T1 - Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P3) and lack a PtdIns(3,4,5)P3 response to cytokines and chemotactic factors; effects reversed by imatinib [9]

AU - Hamzah, H. G.

AU - Pierce, A.

AU - Stewart, W. A.

AU - Downes, C. Peter

AU - Gray, A.

AU - Irvine, A.

AU - Spooncer, E.

AU - Whetton, A. D.

PY - 2005/8/18

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DO - 10.1038/sj.leu.2403919

M3 - Letter

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AN - SCOPUS:27144454373

SN - 0887-6924

VL - 19

SP - 1851

EP - 1853

JO - Leukemia

JF - Leukemia

IS - 10