TY - JOUR
T1 - Clarification of route specific impurities found in methylamphetamine synthesised using the Birch method
AU - Kunalan, Vanitha
AU - Kerr, William J.
AU - NicDaéid, Niamh
PY - 2012/11/30
Y1 - 2012/11/30
N2 - This paper focuses on the determination of route specific impurities produced when methylamphetamine is synthesised using the Birch reduction. Previous work available in the scientific literature reported only one route specific impurity using ephedrine hydrochloride as the starting material. In this paper we investigated the impurity profiles of methylamphetamine produced from both the salt and base forms of ephedrine and pseudoephedrine. A new previously unreported route specific impurity was revealed as was the potential absence of the previously reported impurity in the profile of samples prepared from the free base.
AB - This paper focuses on the determination of route specific impurities produced when methylamphetamine is synthesised using the Birch reduction. Previous work available in the scientific literature reported only one route specific impurity using ephedrine hydrochloride as the starting material. In this paper we investigated the impurity profiles of methylamphetamine produced from both the salt and base forms of ephedrine and pseudoephedrine. A new previously unreported route specific impurity was revealed as was the potential absence of the previously reported impurity in the profile of samples prepared from the free base.
UR - http://www.scopus.com/inward/record.url?scp=84870291905&partnerID=8YFLogxK
U2 - 10.1016/j.forsciint.2012.10.008
DO - 10.1016/j.forsciint.2012.10.008
M3 - Article
C2 - 23127659
AN - SCOPUS:84870291905
SN - 0379-0738
VL - 223
SP - 321
EP - 329
JO - Forensic Science International
JF - Forensic Science International
IS - 1-3
ER -