Clathrin light chains: arrays of protein motifs that regulate coated-vesicle dynamics

Frances M. Brodsky; Beth L. Hill; Susan L. Acton; Inke Näthke; Darren H. Wong; Sreenivasan Ponnambalam; Peter Parham

doi:10.1016/0968-0004(91)90087-C

Clathrin light chains: arrays of protein motifs that regulate coated-vesicle dynamics

Frances M. Brodsky, Beth L. Hill, Susan L. Acton, Inke Näthke, Darren H. Wong, Sreenivasan Ponnambalam, Peter Parham

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Abstract

Polymerization of clathrin triskelions into clathrin coats and subsequent disassembly by the heat shock protein hsc70 control receptor-mediated pathways of intracellular transport. The clathrin light chains are major regulatory elements in these processes. These polypeptides consist of linear arrays of functional domains with distinctive sequence motifs. Comparison of unicellular and multicellular eukaryotes reveals differences in the numbers of clathrin light chains and in the functional domains they contain.

Original language	English
Pages (from-to)	208-213
Number of pages	6
Journal	Trends in Biochemical Sciences
Volume	16
DOIs	https://doi.org/10.1016/0968-0004(91)90087-C
Publication status	Published - 1991

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title = "Clathrin light chains: arrays of protein motifs that regulate coated-vesicle dynamics",

abstract = "Polymerization of clathrin triskelions into clathrin coats and subsequent disassembly by the heat shock protein hsc70 control receptor-mediated pathways of intracellular transport. The clathrin light chains are major regulatory elements in these processes. These polypeptides consist of linear arrays of functional domains with distinctive sequence motifs. Comparison of unicellular and multicellular eukaryotes reveals differences in the numbers of clathrin light chains and in the functional domains they contain.",

author = "Brodsky, {Frances M.} and Hill, {Beth L.} and Acton, {Susan L.} and Inke N{\"a}thke and Wong, {Darren H.} and Sreenivasan Ponnambalam and Peter Parham",

year = "1991",

doi = "10.1016/0968-0004(91)90087-C",

language = "English",

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pages = "208--213",

journal = "Trends in Biochemical Sciences",

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T2 - arrays of protein motifs that regulate coated-vesicle dynamics

AU - Brodsky, Frances M.

AU - Hill, Beth L.

AU - Acton, Susan L.

AU - Näthke, Inke

AU - Wong, Darren H.

AU - Ponnambalam, Sreenivasan

AU - Parham, Peter

PY - 1991

Y1 - 1991

N2 - Polymerization of clathrin triskelions into clathrin coats and subsequent disassembly by the heat shock protein hsc70 control receptor-mediated pathways of intracellular transport. The clathrin light chains are major regulatory elements in these processes. These polypeptides consist of linear arrays of functional domains with distinctive sequence motifs. Comparison of unicellular and multicellular eukaryotes reveals differences in the numbers of clathrin light chains and in the functional domains they contain.

AB - Polymerization of clathrin triskelions into clathrin coats and subsequent disassembly by the heat shock protein hsc70 control receptor-mediated pathways of intracellular transport. The clathrin light chains are major regulatory elements in these processes. These polypeptides consist of linear arrays of functional domains with distinctive sequence motifs. Comparison of unicellular and multicellular eukaryotes reveals differences in the numbers of clathrin light chains and in the functional domains they contain.

U2 - 10.1016/0968-0004(91)90087-C

DO - 10.1016/0968-0004(91)90087-C

M3 - Article

C2 - 1909824

SN - 0968-0004

VL - 16

SP - 208

EP - 213

JO - Trends in Biochemical Sciences

JF - Trends in Biochemical Sciences

ER -

Clathrin light chains: arrays of protein motifs that regulate coated-vesicle dynamics

Abstract

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