Clinical and veterinary trypanocidal benzoxaboroles target CPSF3

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• Finished

  Wellcome Centre for Anti-Infectives Research

  Baragana, B. (Investigator), Cook, S. (Investigator), De Rycker, M. (Investigator), Fairlamb, A. (Investigator), Ferguson, M. (Investigator), Field, M. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator), Horn, D. (Investigator), Lee, M. (Investigator), Pawlowic, M. C. (Investigator), Read, K. (Investigator), Wyatt, P. (Investigator) & Wyllie, S. (Investigator)

  1/04/17 → 1/04/25

  Project: Research

  • Drug Discovery 100%
  • Trypanosoma Cruzi (T. cruzi) 90%
  • Chagas Disease 71%
  • Trypanosoma Cruzi 69%
  • Visceral Leishmaniasis 64%

• Chemical Biology: Leveraging Phenotypic Hits Against Kinetoplastids (Strategic Grant)

  Fairlamb, A. (Investigator), Field, M. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator), Horn, D. (Investigator) & Wyatt, P. (Investigator)

  1/01/15 → 31/12/20

  Project: Research

  • Visceral Leishmaniasis 100%
  • Drug Discovery 96%
  • Leishmania Donovani 82%
  • Chagas Disease 74%
  • Drug Target 69%

• High-Throughput Decoding of Virulence Mechanisms in African Trypanosomes (Senior Investigator Award)

  Horn, D. (Investigator)

  1/09/13 → 29/02/20

  Project: Research

  • Trypanosoma 100%
  • Trypanosoma Brucei 73%
  • African Trypanosomes 70%
  • Trypanosome 61%
  • Spike Glycoprotein 43%