TY - JOUR
T1 - Clinical application of skin substitutes
AU - Damodaran, Gopinath
AU - Syed, Mobin
AU - Leigh, Irene
AU - Myers, Simon
AU - Navsaria, Harshad
N1 - Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2008
Y1 - 2008
N2 - There has been a perpetual demand for skin and its replacements, which has fuelled advances in the development of novel skin substitutes. The field of skin bioengineering has made mammoth progress in the last 30 years, helped by the advances in the biotechnology and understanding of wound-healing mechanisms. The options for skin substitutes currently range from the cadaveric skin of the past to a number of epidermal, dermal and composite constructs. This review focuses on the clinical applications of various skin substitutes currently available, looking into their advantages and disadvantages and the scope for future improvements.
AB - There has been a perpetual demand for skin and its replacements, which has fuelled advances in the development of novel skin substitutes. The field of skin bioengineering has made mammoth progress in the last 30 years, helped by the advances in the biotechnology and understanding of wound-healing mechanisms. The options for skin substitutes currently range from the cadaveric skin of the past to a number of epidermal, dermal and composite constructs. This review focuses on the clinical applications of various skin substitutes currently available, looking into their advantages and disadvantages and the scope for future improvements.
UR - http://www.scopus.com/inward/record.url?scp=55249120463&partnerID=8YFLogxK
U2 - 10.1586/17469872.3.3.345
DO - 10.1586/17469872.3.3.345
M3 - Article
AN - SCOPUS:55249120463
SN - 1746-9872
VL - 3
SP - 345
EP - 356
JO - Expert Review of Dermatology
JF - Expert Review of Dermatology
IS - 3
ER -