Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma

Natalia Hernandez-Pacheco; Mario Gorenjak; Staša Jurgec; Almudena Corrales; Andrea Jorgensen; Leila Karimi; Susanne J. Vijverberg; Vojko Berce; Maximilian Schieck; Marialbert Acosta-Herrera; Martin Kerick; Lesly-Anne Samedy-Bates; Roger Tavendale; Jesús Villar; Somnath Mukhopadhyay; Munir Pirmohamed; Katia M. C. Verhamme; Michael Kabesch; Daniel B. Hawcutt; Steve Turner; Colin N. Palmer; Esteban G. Burchard; Anke H. Maitland-van der Zee; Carlos Flores; Uroš Potočnik; Maria Pino-Yanes

doi:10.1111/all.14552

Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma

, Natalia Hernandez-Pacheco, Mario Gorenjak, Staša Jurgec, Almudena Corrales, Andrea Jorgensen, Leila Karimi, Susanne J. Vijverberg, Vojko Berce, Maximilian Schieck, Marialbert Acosta-Herrera, Martin Kerick, Lesly-Anne Samedy-Bates, Roger Tavendale, Jesús Villar, Somnath Mukhopadhyay, Munir Pirmohamed, Katia M. C. Verhamme, Michael Kabesch, Daniel B. HawcuttSteve Turner, Colin N. Palmer, Esteban G. Burchard, Anke H. Maitland-van der Zee, Carlos Flores, Uroš Potočnik, Maria Pino-Yanes

Research output: Contribution to journal › Letter › peer-review

Original language	English
Number of pages	6
Journal	Allergy
Early online date	12 Aug 2020
DOIs	https://doi.org/10.1111/all.14552
Publication status	E-pub ahead of print - 12 Aug 2020

Keywords

asthma treatment
childhood asthma
exacerbations
genetic polymorphism
pharmacogenomics

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10.1111/all.14552

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Embargo ends: 12/08/21

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The Tayside Bioresource: Leveraging Electronic Medical Records to Deliver Personalised Medicine (Biomedical Resource Grant)
Colhoun, H., Connell, J., Doney, A., Dow, E., Morris, A., Palmer, C., Pearson, E., Sullivan, F. & Treweek, S.
Wellcome Trust
1/02/13 → 31/10/15
Project: Research

Cite this

, Hernandez-Pacheco, N., Gorenjak, M., Jurgec, S., Corrales, A., Jorgensen, A., Karimi, L., Vijverberg, S. J., Berce, V., Schieck, M., Acosta-Herrera, M., Kerick, M., Samedy-Bates, L-A., Tavendale, R., Villar, J., Mukhopadhyay, S., Pirmohamed, M., Verhamme, K. M. C., Kabesch, M., ... Pino-Yanes, M. (2020). Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma. Allergy. https://doi.org/10.1111/all.14552

Hernandez-Pacheco, Natalia ; Gorenjak, Mario ; Jurgec, Staša ; Corrales, Almudena ; Jorgensen, Andrea ; Karimi, Leila ; Vijverberg, Susanne J. ; Berce, Vojko ; Schieck, Maximilian ; Acosta-Herrera, Marialbert ; Kerick, Martin ; Samedy-Bates, Lesly-Anne ; Tavendale, Roger ; Villar, Jesús ; Mukhopadhyay, Somnath ; Pirmohamed, Munir ; Verhamme, Katia M. C. ; Kabesch, Michael ; Hawcutt, Daniel B. ; Turner, Steve ; Palmer, Colin N. ; Burchard, Esteban G. ; Maitland-van der Zee, Anke H. ; Flores, Carlos ; Potočnik, Uroš ; Pino-Yanes, Maria. / Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma. In: Allergy. 2020.

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title = "Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma",

keywords = "asthma treatment, childhood asthma, exacerbations, genetic polymorphism, pharmacogenomics",

author = "Natalia Hernandez-Pacheco and Mario Gorenjak and Sta{\v s}a Jurgec and Almudena Corrales and Andrea Jorgensen and Leila Karimi and Vijverberg, {Susanne J.} and Vojko Berce and Maximilian Schieck and Marialbert Acosta-Herrera and Martin Kerick and Lesly-Anne Samedy-Bates and Roger Tavendale and Jes{\'u}s Villar and Somnath Mukhopadhyay and Munir Pirmohamed and Verhamme, {Katia M. C.} and Michael Kabesch and Hawcutt, {Daniel B.} and Steve Turner and Palmer, {Colin N.} and Burchard, {Esteban G.} and {Maitland-van der Zee}, {Anke H.} and Carlos Flores and Uro{\v s} Poto{\v c}nik and Maria Pino-Yanes",

note = "National Heart, Lung, and Blood Institute of the National Institute of Health. Grant Numbers: R01HL117004, X01HL134589 Slovenian Research Agency. Grant Number: P3‐0067 National Institute of Environmental Health Sciences. Grant Number: R01ES015794 NHS Chair of Pharmacogenetics via the UK Department of Health GlaxoSmithKline foundation Ministry of Education, Science and Sport Slovenia. Grant Number: C3330‐16‐500106 Utrecht Institute for Pharmaceutical Sciences Instituto de Salud Carlos III (ISCIII). Grant Numbers: AC15/00015, FI16/00136 PT17/0019 ERACoSysMed 1st Joint Transnational Call. Grant Number: SysPharmPedia Spanish Ministry of Economy, Industry, and Competitiveness Sandler Family Foundation American Asthma Foundation RWJF Amos Medical Faculty Development Program NHS Research Scotland Wellcome Trust Biomedical Resource. Grant Number: 099177/Z/12/Z ZonMw. Grant Number: 113201006 European Regional Development Fund (ERDF). Grant Number: PT17/0019 SAF2017‐83417R",

year = "2020",

month = aug,

day = "12",

doi = "10.1111/all.14552",

language = "English",

journal = "Allergy",

issn = "0105-4538",

publisher = "Wiley",

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Hernandez-Pacheco, N, Gorenjak, M, Jurgec, S, Corrales, A, Jorgensen, A, Karimi, L, Vijverberg, SJ, Berce, V, Schieck, M, Acosta-Herrera, M, Kerick, M, Samedy-Bates, L-A, Tavendale, R, Villar, J, Mukhopadhyay, S, Pirmohamed, M, Verhamme, KMC, Kabesch, M, Hawcutt, DB, Turner, S, Palmer, CN, Burchard, EG, Maitland-van der Zee, AH, Flores, C & Potočnik, U & Pino-Yanes, M 2020, 'Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma', Allergy. https://doi.org/10.1111/all.14552

Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma. /; Hernandez-Pacheco, Natalia; Gorenjak, Mario; Jurgec, Staša; Corrales, Almudena; Jorgensen, Andrea; Karimi, Leila; Vijverberg, Susanne J.; Berce, Vojko; Schieck, Maximilian; Acosta-Herrera, Marialbert; Kerick, Martin; Samedy-Bates, Lesly-Anne; Tavendale, Roger; Villar, Jesús; Mukhopadhyay, Somnath; Pirmohamed, Munir; Verhamme, Katia M. C.; Kabesch, Michael; Hawcutt, Daniel B.; Turner, Steve; Palmer, Colin N.; Burchard, Esteban G.; Maitland-van der Zee, Anke H.; Flores, Carlos; Potočnik, Uroš; Pino-Yanes, Maria (Lead / Corresponding author).

In: Allergy, 12.08.2020.

Research output: Contribution to journal › Letter › peer-review

TY - JOUR

T1 - Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma

AU - Hernandez-Pacheco, Natalia

AU - Gorenjak, Mario

AU - Jurgec, Staša

AU - Corrales, Almudena

AU - Jorgensen, Andrea

AU - Karimi, Leila

AU - Vijverberg, Susanne J.

AU - Berce, Vojko

AU - Schieck, Maximilian

AU - Acosta-Herrera, Marialbert

AU - Kerick, Martin

AU - Samedy-Bates, Lesly-Anne

AU - Tavendale, Roger

AU - Villar, Jesús

AU - Mukhopadhyay, Somnath

AU - Pirmohamed, Munir

AU - Verhamme, Katia M. C.

AU - Kabesch, Michael

AU - Hawcutt, Daniel B.

AU - Turner, Steve

AU - Palmer, Colin N.

AU - Burchard, Esteban G.

AU - Maitland-van der Zee, Anke H.

AU - Flores, Carlos

AU - Potočnik, Uroš

AU - Pino-Yanes, Maria

N1 - National Heart, Lung, and Blood Institute of the National Institute of Health. Grant Numbers: R01HL117004, X01HL134589 Slovenian Research Agency. Grant Number: P3‐0067 National Institute of Environmental Health Sciences. Grant Number: R01ES015794 NHS Chair of Pharmacogenetics via the UK Department of Health GlaxoSmithKline foundation Ministry of Education, Science and Sport Slovenia. Grant Number: C3330‐16‐500106 Utrecht Institute for Pharmaceutical Sciences Instituto de Salud Carlos III (ISCIII). Grant Numbers: AC15/00015, FI16/00136 PT17/0019 ERACoSysMed 1st Joint Transnational Call. Grant Number: SysPharmPedia Spanish Ministry of Economy, Industry, and Competitiveness Sandler Family Foundation American Asthma Foundation RWJF Amos Medical Faculty Development Program NHS Research Scotland Wellcome Trust Biomedical Resource. Grant Number: 099177/Z/12/Z ZonMw. Grant Number: 113201006 European Regional Development Fund (ERDF). Grant Number: PT17/0019 SAF2017‐83417R

PY - 2020/8/12

Y1 - 2020/8/12

KW - asthma treatment

KW - childhood asthma

KW - exacerbations

KW - genetic polymorphism

KW - pharmacogenomics

UR - http://www.scopus.com/inward/record.url?scp=85090972491&partnerID=8YFLogxK

U2 - 10.1111/all.14552

DO - 10.1111/all.14552

M3 - Letter

C2 - 32786158

JO - Allergy

JF - Allergy

SN - 0105-4538

ER -

Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma

Keywords

Access to Document

Embargoed Document

The Tayside Bioresource: Leveraging Electronic Medical Records to Deliver Personalised Medicine (Biomedical Resource Grant)

Cite this