@article{92b800d8ffb1417da9790e3a8e23f57b,
title = "Combined indocyanine green and quantitative perfusion assessment with hyperspectral imaging during colorectal resections",
abstract = "Anastomotic insufficiencies still represent one of the most severe complications in colorectal surgery. Since tissue perfusion highly affects anastomotic healing, its objective assessment is an unmet clinical need. Indocyanine green-based fluorescence angiography (ICG-FA) and hyperspectral imaging (HSI) have received great interest in recent years but surgeons have to decide between both techniques. For the first time, two data processing pipelines capable of reconstructing an ICG-FA correlating signal from hyperspectral data were developed. Results were technically evaluated and compared to ground truth data obtained during colorectal resections. In 87% of 46 data sets, the reconstructed images resembled the ground truth data. The combined applicability of ICG-FA and HSI within one imaging system might provide supportive and complementary information about tissue vascularization, shorten surgery time, and reduce perioperative mortality.",
author = "A. Pfahl and Radmacher, {G. K.} and H. K{\"o}hler and M. Maktabi and T. Neumuth and A. Melzer and I. Gockel and C. Chalopin and B. Jansen-Winkeln",
note = "Funding Information: The mapping of KFS 5 would not have been possible without the kind permission of the landowners, Mr. and Mrs. Bester. The fieldwork was funded principally by the French Institute of South Africa (IFAS). Some of the laboratory work was sponsored by the Deutsche Forschungsgemeinschaft (SFB 389), The Wenner-Gren Foundation, and the National Research Foundation of South Africa. Heritage Western Cape kindly permitted the export and analyses of the vitrified dung from KFS5. We would like to thank David Gaimster, London, and Antonius J{\"u}rgens, Z{\"u}lpich, for their expert help in identifying the Bartmann fragment; Susanne Greiff, Mainz, for the preliminary analysis of the vitrified dung sample; and Andrew Kandel, Cape Town, for his help in identifying the lithic raw materials. Our thanks go to the two reviewers (John Kinahan and another who preferred to remain anonymous) who helped to vastly improve this article. Needless to say, any errors in the paper remain the responsibility of the authors. Special thanks to Kathleen Schulz for tracking down the historical records of early farms on the Vredenburg Peninsula, and to Julie Morin and Feldrik Rivat for drawing the lithic artefacts. Publisher Copyright: {\textcopyright} 2022 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement",
year = "2022",
month = may,
day = "1",
doi = "10.1364/BOE.452076",
language = "English",
volume = "13",
pages = "3145--3160",
journal = "Biomedical Optics Express",
issn = "2156-7085",
publisher = "Optical Society of America",
number = "5",
}