Combining precision medicine and prophylaxis in oesophageal squamous cell carcinoma

Mark Baxter; Lindsay Spender; Russell Petty

doi:10.1038/s41416-020-01057-3

Combining precision medicine and prophylaxis in oesophageal squamous cell carcinoma

Mark Baxter, Lindsay Spender, Russell Petty (Lead / Corresponding author)

Research output: Contribution to journal › Editorial › peer-review

3 Citations (Scopus)

61 Downloads (Pure)

Abstract

A trial update confirms improved survival for prophylactic elective nodal irradiation and addition of erlotinib to definitive chemoradiotherapy in oesophageal squamous cell carcinoma (ESCC). High tumour EGFR protein expression shows promise to identify those who will benefit from erlotinib. This represents therapeutic progress, and has wider relevance for precision medicine strategies in ESCC.

Original language	English
Pages (from-to)	1585-1587
Number of pages	3
Journal	British Journal of Cancer
Volume	123
Issue number	11
Early online date	22 Sept 2020
DOIs	https://doi.org/10.1038/s41416-020-01057-3
Publication status	Published - 24 Nov 2020

Keywords

Oesophageal cancer

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1038/s41416-020-01057-3Licence: CC BY

Final Published VersionFinal published version, 447 KBLicence: CC BY

Cite this

@article{e467a26ffbf643e28ecb2e8b08a35c20,

title = "Combining precision medicine and prophylaxis in oesophageal squamous cell carcinoma",

abstract = "A trial update confirms improved survival for prophylactic elective nodal irradiation and addition of erlotinib to definitive chemoradiotherapy in oesophageal squamous cell carcinoma (ESCC). High tumour EGFR protein expression shows promise to identify those who will benefit from erlotinib. This represents therapeutic progress, and has wider relevance for precision medicine strategies in ESCC.",

keywords = "Oesophageal cancer",

author = "Mark Baxter and Lindsay Spender and Russell Petty",

year = "2020",

month = nov,

day = "24",

doi = "10.1038/s41416-020-01057-3",

language = "English",

volume = "123",

pages = "1585--1587",

journal = "British Journal of Cancer",

issn = "0007-0920",

publisher = "Springer Nature",

number = "11",

}

TY - JOUR

T1 - Combining precision medicine and prophylaxis in oesophageal squamous cell carcinoma

AU - Baxter, Mark

AU - Spender, Lindsay

AU - Petty, Russell

PY - 2020/11/24

Y1 - 2020/11/24

N2 - A trial update confirms improved survival for prophylactic elective nodal irradiation and addition of erlotinib to definitive chemoradiotherapy in oesophageal squamous cell carcinoma (ESCC). High tumour EGFR protein expression shows promise to identify those who will benefit from erlotinib. This represents therapeutic progress, and has wider relevance for precision medicine strategies in ESCC.

AB - A trial update confirms improved survival for prophylactic elective nodal irradiation and addition of erlotinib to definitive chemoradiotherapy in oesophageal squamous cell carcinoma (ESCC). High tumour EGFR protein expression shows promise to identify those who will benefit from erlotinib. This represents therapeutic progress, and has wider relevance for precision medicine strategies in ESCC.

KW - Oesophageal cancer

UR - http://www.scopus.com/inward/record.url?scp=85091161562&partnerID=8YFLogxK

U2 - 10.1038/s41416-020-01057-3

DO - 10.1038/s41416-020-01057-3

M3 - Editorial

C2 - 32958821

SN - 0007-0920

VL - 123

SP - 1585

EP - 1587

JO - British Journal of Cancer

JF - British Journal of Cancer

IS - 11

ER -

Combining precision medicine and prophylaxis in oesophageal squamous cell carcinoma

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Identifying and Validating Predictive Biomarkers in Advanced Oesophagael Adenocarcinoma - A Springboard to REAListic Medicine (BE-REAL)

Understanding Resistance to Targeted Therapies in Oesophageal Squamous Cell Carcinoma as a Foundation to Developing New Precision Medicine Approaches

Cite this

Combining precision medicine and prophylaxis in oesophageal squamous cell carcinoma

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Projects

Identifying and Validating Predictive Biomarkers in Advanced Oesophagael Adenocarcinoma - A Springboard to REAListic Medicine (BE-REAL)

Understanding Resistance to Targeted Therapies in Oesophageal Squamous Cell Carcinoma as a Foundation to Developing New Precision Medicine Approaches

Cite this