Community standards for open cell migration data

Alejandra N. Gonzalez-Beltran, Paola Masuzzo, Christophe Ampe, Gert-Jan Bakker, Sébastien Besson, Robert H. Eibl, Peter Friedl, Matthias Gunzer, Mark Kittisopikul, Sylvia E. Le Dévédec, Simone Leo, Josh Moore, Yael Paran, Jaime Prilusky, Philippe Rocca-Serra, Philippe Roudot, Marc Schuster, Gwendolien Sergeant, Staffan Strömblad, Jason R. SwedlowMerijn van Erp, Marleen Van Troys, Assaf Zaritsky, Susanna-Assunta Sansone, Lennart Martens

Research output: Contribution to journalReview article

14 Downloads (Pure)

Abstract

Cell migration research has become a high-content field. However, the quantitative information encapsulated in these complex and high-dimensional datasets is not fully exploited owing to the diversity of experimental protocols and non-standardized output formats. In addition, typically the datasets are not open for reuse. Making the data open and Findable, Accessible, Interoperable, and Reusable (FAIR) will enable meta-analysis, data integration, and data mining. Standardized data formats and controlled vocabularies are essential for building a suitable infrastructure for that purpose but are not available in the cell migration domain. We here present standardization efforts by the Cell Migration Standardisation Organisation (CMSO), an open community-driven organization to facilitate the development of standards for cell migration data. This work will foster the development of improved algorithms and tools and enable secondary analysis of public datasets, ultimately unlocking new knowledge of the complex biological process of cell migration.

Original languageEnglish
Article numbergiaa041
Pages (from-to)1-11
Number of pages11
JournalGigaScience
Volume9
Issue number5
Early online date12 May 2020
DOIs
Publication statusPublished - May 2020

Keywords

  • cell migration
  • data standards
  • metadata
  • CMSO
  • MIACME
  • biotrcks
  • frictionless data pacakge
  • FAIR data
  • biotracks
  • frictionless data package

Fingerprint Dive into the research topics of 'Community standards for open cell migration data'. Together they form a unique fingerprint.

  • Cite this

    Gonzalez-Beltran, A. N., Masuzzo, P., Ampe, C., Bakker, G-J., Besson, S., Eibl, R. H., Friedl, P., Gunzer, M., Kittisopikul, M., Le Dévédec, S. E., Leo, S., Moore, J., Paran, Y., Prilusky, J., Rocca-Serra, P., Roudot, P., Schuster, M., Sergeant, G., Strömblad, S., ... Martens, L. (2020). Community standards for open cell migration data. GigaScience, 9(5), 1-11. [giaa041]. https://doi.org/10.1093/gigascience/giaa041