Comparative compositions of cell surface glycoconjugates isolated from Trypanosoma cruzi epimastigotes

TY - JOUR

T1 - Comparative compositions of cell surface glycoconjugates isolated from Trypanosoma cruzi epimastigotes

AU - Ferguson, Michael A. J.

AU - Snary, David

AU - Allen, Anthony K.

PY - 1985/9/27

Y1 - 1985/9/27

N2 - Cell surface glycoconjugates of epimastigotes of Trypanosoma cruzi have been isolated and analyzed to give their amino acid and carbohydrate compositions. Those which have been investigated are a complex of three closely associated glycoproteins, GP24, GP31, GP37, and a lipopeptidophosphoglycan. The GP24-GP31-GP37 complex has an unusual amino acid composition with very low levels of hydrophobic amino acids, it contains 56% (w/w) carbohydrate, with mannose, galactose and glucosamine (presumably N-acetyl) being present in approximately equal quantities. The lipopeptidophosphoglycan also has low levels of hydrophobic amino acids and contains equal levels of mannose and galactose together with lesser amounts of (N-acetyl) glucosamine. The glycoconjugates are contrasted and compared with two other previously characterised cell surface glycoproteins (GP25 and GP72) from T. cruzi.

AB - Cell surface glycoconjugates of epimastigotes of Trypanosoma cruzi have been isolated and analyzed to give their amino acid and carbohydrate compositions. Those which have been investigated are a complex of three closely associated glycoproteins, GP24, GP31, GP37, and a lipopeptidophosphoglycan. The GP24-GP31-GP37 complex has an unusual amino acid composition with very low levels of hydrophobic amino acids, it contains 56% (w/w) carbohydrate, with mannose, galactose and glucosamine (presumably N-acetyl) being present in approximately equal quantities. The lipopeptidophosphoglycan also has low levels of hydrophobic amino acids and contains equal levels of mannose and galactose together with lesser amounts of (N-acetyl) glucosamine. The glycoconjugates are contrasted and compared with two other previously characterised cell surface glycoproteins (GP25 and GP72) from T. cruzi.

UR - https://www.scopus.com/pages/publications/0021927452

U2 - 10.1016/0304-4165(85)90290-9

DO - 10.1016/0304-4165(85)90290-9

M3 - Article

AN - SCOPUS:0021927452

SN - 0304-4165

VL - 842

SP - 39

EP - 44

JO - BBA - General Subjects

JF - BBA - General Subjects

IS - 1

ER -