Comparative evaluation of calcium hypochlorite and sodium hypochlorite on soft-tissue dissolution

Arindam Dutta, William P. Saunders

    Research output: Contribution to journalArticle

    31 Citations (Scopus)

    Abstract

    Introduction: The aim of this study was to compare in vitro the tissue-dissolution properties of 5% and 10% calcium hypochlorite (Ca(OCl) ) with two concentrations (1.36% and 4.65%) of proprietary sodium hypochlorite (NaOCl) on bovine muscle tissue. Methods: The available chlorine concentration of each solution was determined using iodometric titration. Tissue specimens from bovine muscle were weight adjusted (50 ± 5 mg). Ten tissue specimens in each group were immersed in 5 mL each test solution, removed after 5 minutes, blotted dry, and weighed. The process was repeated every 5 minutes with a fresh 5-mL aliquot of the test solution for 60 minutes or until complete tissue dissolution, whichever was quickest. The percentage weight loss of the specimens was calculated over the experimental period. Results: Available chlorine concentrations of the irrigants ranged from 1.36% to 4.65%. All solutions dissolved tissue completely after 60 minutes except 5% Ca(OCl) (99.4% dissolution). Between the 35- and 60-minute test readings, there were no significant differences between the solutions. Chlorax (4.65% NaOCl) (Cerkamed Group, Nisko, Poland) dissolved tissue quicker during the first 35 minutes (P <.05). In this period, the weight loss with 10% Ca(OCl) differed from Chlorax at all time intervals except at 5 and 35 minutes (P <.05); 5% Ca(OCl) showed no significant differences with 10% Ca(OCl) and Tesco bleach (1.36% NaOCl) (Tesco Stores Ltd, Chestnut, UK) in the first 35 minutes except at the 5-minute measurement. Conclusions: Within the limitations of this study, Chlorax (4.65% NaOCl) dissolved tissue faster than the Ca(OCl) solutions and Tesco thin bleach (1.36% NaOCl) over the first 35 minutes, but there were no significant differences among the solutions thereafter.
    Original languageEnglish
    Pages (from-to)1395-1398
    Number of pages4
    JournalJournal of Endodontics
    Volume38
    Issue number10
    DOIs
    Publication statusPublished - 2012

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    Sodium Hypochlorite
    Chlorine
    Weight Loss
    Muscles
    Poland
    calcium hypochlorite
    Reading
    Weights and Measures

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    Dutta, Arindam ; Saunders, William P. / Comparative evaluation of calcium hypochlorite and sodium hypochlorite on soft-tissue dissolution. In: Journal of Endodontics. 2012 ; Vol. 38, No. 10. pp. 1395-1398.
    @article{db265c87415e45c292b2e8c2a8f1d735,
    title = "Comparative evaluation of calcium hypochlorite and sodium hypochlorite on soft-tissue dissolution",
    abstract = "Introduction: The aim of this study was to compare in vitro the tissue-dissolution properties of 5{\%} and 10{\%} calcium hypochlorite (Ca(OCl) ) with two concentrations (1.36{\%} and 4.65{\%}) of proprietary sodium hypochlorite (NaOCl) on bovine muscle tissue. Methods: The available chlorine concentration of each solution was determined using iodometric titration. Tissue specimens from bovine muscle were weight adjusted (50 ± 5 mg). Ten tissue specimens in each group were immersed in 5 mL each test solution, removed after 5 minutes, blotted dry, and weighed. The process was repeated every 5 minutes with a fresh 5-mL aliquot of the test solution for 60 minutes or until complete tissue dissolution, whichever was quickest. The percentage weight loss of the specimens was calculated over the experimental period. Results: Available chlorine concentrations of the irrigants ranged from 1.36{\%} to 4.65{\%}. All solutions dissolved tissue completely after 60 minutes except 5{\%} Ca(OCl) (99.4{\%} dissolution). Between the 35- and 60-minute test readings, there were no significant differences between the solutions. Chlorax (4.65{\%} NaOCl) (Cerkamed Group, Nisko, Poland) dissolved tissue quicker during the first 35 minutes (P <.05). In this period, the weight loss with 10{\%} Ca(OCl) differed from Chlorax at all time intervals except at 5 and 35 minutes (P <.05); 5{\%} Ca(OCl) showed no significant differences with 10{\%} Ca(OCl) and Tesco bleach (1.36{\%} NaOCl) (Tesco Stores Ltd, Chestnut, UK) in the first 35 minutes except at the 5-minute measurement. Conclusions: Within the limitations of this study, Chlorax (4.65{\%} NaOCl) dissolved tissue faster than the Ca(OCl) solutions and Tesco thin bleach (1.36{\%} NaOCl) over the first 35 minutes, but there were no significant differences among the solutions thereafter.",
    author = "Arindam Dutta and Saunders, {William P.}",
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    Comparative evaluation of calcium hypochlorite and sodium hypochlorite on soft-tissue dissolution. / Dutta, Arindam; Saunders, William P.

    In: Journal of Endodontics, Vol. 38, No. 10, 2012, p. 1395-1398.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Comparative evaluation of calcium hypochlorite and sodium hypochlorite on soft-tissue dissolution

    AU - Dutta, Arindam

    AU - Saunders, William P.

    N1 - Copyright 2012 Elsevier B.V., All rights reserved.

    PY - 2012

    Y1 - 2012

    N2 - Introduction: The aim of this study was to compare in vitro the tissue-dissolution properties of 5% and 10% calcium hypochlorite (Ca(OCl) ) with two concentrations (1.36% and 4.65%) of proprietary sodium hypochlorite (NaOCl) on bovine muscle tissue. Methods: The available chlorine concentration of each solution was determined using iodometric titration. Tissue specimens from bovine muscle were weight adjusted (50 ± 5 mg). Ten tissue specimens in each group were immersed in 5 mL each test solution, removed after 5 minutes, blotted dry, and weighed. The process was repeated every 5 minutes with a fresh 5-mL aliquot of the test solution for 60 minutes or until complete tissue dissolution, whichever was quickest. The percentage weight loss of the specimens was calculated over the experimental period. Results: Available chlorine concentrations of the irrigants ranged from 1.36% to 4.65%. All solutions dissolved tissue completely after 60 minutes except 5% Ca(OCl) (99.4% dissolution). Between the 35- and 60-minute test readings, there were no significant differences between the solutions. Chlorax (4.65% NaOCl) (Cerkamed Group, Nisko, Poland) dissolved tissue quicker during the first 35 minutes (P <.05). In this period, the weight loss with 10% Ca(OCl) differed from Chlorax at all time intervals except at 5 and 35 minutes (P <.05); 5% Ca(OCl) showed no significant differences with 10% Ca(OCl) and Tesco bleach (1.36% NaOCl) (Tesco Stores Ltd, Chestnut, UK) in the first 35 minutes except at the 5-minute measurement. Conclusions: Within the limitations of this study, Chlorax (4.65% NaOCl) dissolved tissue faster than the Ca(OCl) solutions and Tesco thin bleach (1.36% NaOCl) over the first 35 minutes, but there were no significant differences among the solutions thereafter.

    AB - Introduction: The aim of this study was to compare in vitro the tissue-dissolution properties of 5% and 10% calcium hypochlorite (Ca(OCl) ) with two concentrations (1.36% and 4.65%) of proprietary sodium hypochlorite (NaOCl) on bovine muscle tissue. Methods: The available chlorine concentration of each solution was determined using iodometric titration. Tissue specimens from bovine muscle were weight adjusted (50 ± 5 mg). Ten tissue specimens in each group were immersed in 5 mL each test solution, removed after 5 minutes, blotted dry, and weighed. The process was repeated every 5 minutes with a fresh 5-mL aliquot of the test solution for 60 minutes or until complete tissue dissolution, whichever was quickest. The percentage weight loss of the specimens was calculated over the experimental period. Results: Available chlorine concentrations of the irrigants ranged from 1.36% to 4.65%. All solutions dissolved tissue completely after 60 minutes except 5% Ca(OCl) (99.4% dissolution). Between the 35- and 60-minute test readings, there were no significant differences between the solutions. Chlorax (4.65% NaOCl) (Cerkamed Group, Nisko, Poland) dissolved tissue quicker during the first 35 minutes (P <.05). In this period, the weight loss with 10% Ca(OCl) differed from Chlorax at all time intervals except at 5 and 35 minutes (P <.05); 5% Ca(OCl) showed no significant differences with 10% Ca(OCl) and Tesco bleach (1.36% NaOCl) (Tesco Stores Ltd, Chestnut, UK) in the first 35 minutes except at the 5-minute measurement. Conclusions: Within the limitations of this study, Chlorax (4.65% NaOCl) dissolved tissue faster than the Ca(OCl) solutions and Tesco thin bleach (1.36% NaOCl) over the first 35 minutes, but there were no significant differences among the solutions thereafter.

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