Abstract
Standard adjuvant chemotherapy for colorectal cancer consists of fluorouracil with folinic acid or levamisole. The large QUASAR randomised trial aimed to investigate (in a two x two design) whether use of a higher dose of folinic acid or addition of levamisole to fluorouracil and folinic acid improved survival.
Original language | English |
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Pages (from-to) | 1588-96 |
Number of pages | 9 |
Journal | Lancet |
Volume | 355 |
Issue number | 9215 |
DOIs | |
Publication status | Published - 6 May 2000 |
Keywords
- Adjuvants, Immunologic
- Antimetabolites, Antineoplastic
- Chemotherapy, Adjuvant
- Colonic Neoplasms
- Drug Therapy, Combination
- Fluorouracil
- Humans
- Leucovorin
- Levamisole
- Neoplasm Recurrence, Local
- Radiotherapy, Adjuvant
- Rectal Neoplasms
- Survival Analysis