Comparison of the specificity of Trk inhibitors in recombinant and neuronal assays

Biochemistry, Genetics and Molecular Biology

• Phosphotransferase 100%
• Kinase 100%
• Neurotrophin 100%
• Receptor Tyrosine Kinase 100%
• Tyrosine Kinase 100%
• Trk Receptor 100%
• Mitogen-Activated Protein Kinase 50%
• Mediator 50%
• Brain-Derived Neurotrophic Factor 50%
• Autophosphorylation 50%
• Tyrosine 50%
• Intracellular Signaling 50%
• Glycogen Synthase Kinase 50%
• Serine 50%
• Threonine 50%
• N-Methyl-D-Aspartic Acid 50%

Keyphrases

• Recombinant 100%
• K252a 100%
• Kinase Activity 66%
• Neurotrophins 66%
• ERK2 66%
• TrkB Receptor 66%
• Tyrosine Kinase Domain 66%
• Serine-threonine Kinase 33%
• Mitogen-activated Protein Kinase 33%
• Tyrosine 33%
• Autophosphorylation 33%
• Intracellular Signaling 33%
• Adapter Protein 33%
• Nervous System 33%
• Neural Plasticity 33%
• New Inhibitors 33%
• TrkB 33%
• Neuronal Development 33%
• Mediated Action 33%
• Neuronal Survival 33%
• Receptor-interacting Protein Kinase 1 (RIPK1) 33%
• PI3K Pathway 33%
• PLCG1 33%
• TrkA 33%

Neuroscience

• K252a 100%
• Receptor 100%
• In Vitro 66%
• Mitogen Activated Protein Kinase 3 66%
• Kinase 66%
• Tyrosine Kinase 66%
• Receptor Tyrosine Kinase 66%
• Neurotrophin 66%
• Trk Receptor 66%
• Mitogen-Activated Protein Kinase 33%
• Nervous System 33%
• N-Methyl-D-Aspartic Acid 33%
• Protein Serine Threonine Kinase 33%
• Intracellular Signaling 33%
• Brain-Derived Neurotrophic Factor 33%
• Neural Development 33%
• Glycogen Synthase Kinase 33%