Conditional deletion of cytochrome P450 oxidoreductase in the liver and gastrointestinal tract: A new model for studying the functions of the P450 system

Keyphrases

• Liver 100%
• Cytochrome P450 Reductase 100%
• Conditional Deletion 100%
• Gastrointestinal Tract 100%
• P450 System 100%
• P450 25%
• Inducer 16%
• 3-methylcholanthrene 16%
• Cytochrome P450 1A1 (CYP1A1) 16%
• Cytochrome P450 (CYP450) 16%
• Gastrointestinal 16%
• Gene Expression 8%
• Null Mice 8%
• Mouse Model 8%
• P450s 8%
• Chemical Toxicity 8%
• Hepatic Cytochrome P450 8%
• Complete Ablation 8%
• Lipid Homeostasis 8%
• β-Naphthoflavone 8%
• Cre Recombinase 8%
• Cytochrome P450 Expression 8%
• Drug Pharmacokinetics 8%
• Fatty Liver 8%
• Toxicokinetics 8%
• Hepatic Lipid Accumulation 8%
• Drug Deposition 8%
• Efficiency Testing 8%
• Drug Loading Capacity 8%
• Tetrachlorodibenzo-p-dioxin 8%
• Null Model 8%
• Hepatic Phenotype 8%

Pharmacology, Toxicology and Pharmaceutical Science

• Cytochrome P450 Reductase 100%
• Cytochrome P450 100%
• Methylcholanthrene 16%
• Cytochrome P450 1A1 16%
• Knockout Mouse 8%
• Chemical Toxicity 8%
• Beta-Naphthoflavone 8%
• Mouse Model 8%
• Fatty Liver 8%
• 2,3,7,8-Tetrachlorodibenzodioxin 8%
• Cre Recombinase 8%
• Pharmacokinetics 8%
• Toxicokinetics 8%