Confirmed Bacillus anthracis infection among persons who inject drugs, Scotland, 2009-2010

Malcolm Booth, Lindsay Donaldson, Xizhong Cui, Junfeng Sun, Stephen Cole, Susan Dailsey, Andrew Hart, Neil Johns, Paul McConnell, Tina McLennan, Benjamin Parcell, Henry Robb, Benjamin Shippey, Malcolm Sim, Charles Wallis, Peter Q. Eichacker (Lead / Corresponding author)

    Research output: Contribution to journalArticlepeer-review

    19 Citations (Scopus)

    Abstract

    In Scotland, the 2009 outbreak of Bacillus anthracis infection among persons who inject drugs resulted in a 28% death rate. To compare nonsurvivors and survivors, we obtained data on 11 nonsurvivors and 16 survivors. Time from B. anthracis exposure to symptoms or hospitalization and skin and limb findings at presentation did not differ between nonsurvivors and survivors. Proportionately more nonsurvivors had histories of excessive alcohol use (p = 0.05) and required vasopressors and/or mechanical ventilation (p=0.01 for each individually). Nonsurvivors also had higher sequential organ failure assessment scores (mean ± SEM) (7.3 ± 0.9 vs. 1.2 ± 0.4, p
    Original languageEnglish
    Pages (from-to)1452-1463
    Number of pages12
    JournalEmerging Infectious Diseases
    Volume20
    Issue number9
    DOIs
    Publication statusPublished - Sep 2014

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