Conformational control of cofactors in nature - functional tetrapyrrole conformations in the photosynthetic reaction centers of purple bacteria.

Stuart A. MacGowan, Mathias O. Senge

Research output: Contribution to journalArticlepeer-review

Abstract

Chemically identical tetrapyrrole cofactors such as hemes and chlorophylls participate in functionally diverse biological roles. An analysis of the available protein structural data for the bacteriochlorophylls in the photosynthetic reaction center gives statistically reliable evidence of the hypothesis that the protein induced cofactor conformation is a modulator of the bio-molecular function of each reaction center. The results serve as a general model to illustrate conformational control of tetrapyrrole cofactors in other proteins.
Original languageEnglish
Pages (from-to)11621-11623
Number of pages3
JournalChemical Communications
Volume47
Issue number42
DOIs
Publication statusPublished - 14 Nov 2011

Fingerprint

Dive into the research topics of 'Conformational control of cofactors in nature - functional tetrapyrrole conformations in the photosynthetic reaction centers of purple bacteria.'. Together they form a unique fingerprint.

Cite this