Contrasting genetic regulation of plant development in wild barley grown in two European environments revealed by nested association mapping

Paul Herzig; Andreas Maurer; Vera Draba; Rajiv Sharma; Fulvia Draicchio; Hazel Bull; Linda Milne; William T. B. Thomas; Andrew J. Flavell; Klaus Pillen

doi:10.1093/jxb/ery002

Contrasting genetic regulation of plant development in wild barley grown in two European environments revealed by nested association mapping

Paul Herzig, Andreas Maurer, Vera Draba, Rajiv Sharma, Fulvia Draicchio, Hazel Bull, Linda Milne, William T. B. Thomas, Andrew J. Flavell, Klaus Pillen (Lead / Corresponding author)

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Abstract

Barley is cultivated more widely than the other major world crops because it adapts well to environmental constraints, such as drought, heat, and day length. To better understand the genetic control of local adaptation in barley, we studied development in the nested association mapping population HEB-25, derived from crossing 25 wild barley accessions with the cultivar 'Barke'. HEB-25 was cultivated in replicated field trials in Dundee (Scotland) and Halle (Germany), differing in regard to day length, precipitation, and temperature. Applying a genome-wide association study, we located 60 and 66 quantitative trait locus (QTL) regions regulating eight plant development traits in Dundee and Halle, respectively. A number of QTLs could be explained by known major genes such as PHOTOPERIOD 1 (Ppd-H1) and FLOWERING LOCUS T (HvFT-1) that regulate plant development. In addition, we observed that developmental traits in HEB-25 were partly controlled via genotype × environment and genotype × donor interactions, defined as location-specific and family-specific QTL effects. Our findings indicate that QTL alleles are available in the wild barley gene pool that show contrasting effects on plant development, which may be deployed to improve adaptation of cultivated barley to future environmental changes.

Original language	English
Pages (from-to)	1517-1531
Number of pages	15
Journal	Journal of Experimental Botany
Volume	69
Issue number	7
Early online date	18 Jan 2018
DOIs	https://doi.org/10.1093/jxb/ery002
Publication status	Published - 16 Mar 2018

Keywords

Cultivated barley (Hordeum vulgare ssp. vulgare)
flowering
genome-wide association study (GWAS)
genotype by donor interaction (GxD)
genotype by environment interaction (GxE)
nested association mapping (NAM)
plant development
quantitative trait locus (QTL)
wild barley (Hordeum vulgare ssp. Spontaneum)

ASJC Scopus subject areas

Physiology
Plant Science

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10.1093/jxb/ery002Licence: CC BY

Final Published Version
© The Author(s) 2018. Published by Oxford University Press on behalf of the Society for Experimental Biology. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Final published version, 623 KBLicence: CC BY

Cite this

@article{1fbb69d37fef4f6eaad418e24b9f33c5,

title = "Contrasting genetic regulation of plant development in wild barley grown in two European environments revealed by nested association mapping",

abstract = "Barley is cultivated more widely than the other major world crops because it adapts well to environmental constraints, such as drought, heat, and day length. To better understand the genetic control of local adaptation in barley, we studied development in the nested association mapping population HEB-25, derived from crossing 25 wild barley accessions with the cultivar 'Barke'. HEB-25 was cultivated in replicated field trials in Dundee (Scotland) and Halle (Germany), differing in regard to day length, precipitation, and temperature. Applying a genome-wide association study, we located 60 and 66 quantitative trait locus (QTL) regions regulating eight plant development traits in Dundee and Halle, respectively. A number of QTLs could be explained by known major genes such as PHOTOPERIOD 1 (Ppd-H1) and FLOWERING LOCUS T (HvFT-1) that regulate plant development. In addition, we observed that developmental traits in HEB-25 were partly controlled via genotype × environment and genotype × donor interactions, defined as location-specific and family-specific QTL effects. Our findings indicate that QTL alleles are available in the wild barley gene pool that show contrasting effects on plant development, which may be deployed to improve adaptation of cultivated barley to future environmental changes.",

keywords = "Cultivated barley (Hordeum vulgare ssp. vulgare), flowering, genome-wide association study (GWAS), genotype by donor interaction (GxD), genotype by environment interaction (GxE), nested association mapping (NAM), plant development, quantitative trait locus (QTL), wild barley (Hordeum vulgare ssp. Spontaneum)",

author = "Paul Herzig and Andreas Maurer and Vera Draba and Rajiv Sharma and Fulvia Draicchio and Hazel Bull and Linda Milne and Thomas, {William T. B.} and Flavell, {Andrew J.} and Klaus Pillen",

note = "This work was financially supported through ERA-CAPS (Expanding the European Research Area in Molecular Plant Sciences) via the German Research Foundation (DFG, grant Pi339/8-1 to Klaus Pillen) and the UK Biotechnology and Biological Sciences Research Council (BBSRC, grant BB/M004856/1 to Andrew J. Flavell) and via the DFG priority program 1530: Flowering time control - from natural variation to crop improvement (grant Pi339/7-1 to Klaus Pillen). We thank Roswitha Ende, Jana M{\"u}glitz, Markus Hinz, Brigitte Schr{\"o}der, Bernd Kollmorgen and various student assistants for excellent technical assistance at the Halle field station and Martin Bruce, Richard Keith Chris Warden and James Simpson for similar support in Dundee. The James Hutton Institute acknowledges the contribution of the Scottish Governments Rural Affairs and the Environment programme towards its funding.",

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AU - Herzig, Paul

AU - Maurer, Andreas

AU - Draba, Vera

AU - Sharma, Rajiv

AU - Draicchio, Fulvia

AU - Bull, Hazel

AU - Milne, Linda

AU - Thomas, William T. B.

AU - Flavell, Andrew J.

AU - Pillen, Klaus

N1 - This work was financially supported through ERA-CAPS (Expanding the European Research Area in Molecular Plant Sciences) via the German Research Foundation (DFG, grant Pi339/8-1 to Klaus Pillen) and the UK Biotechnology and Biological Sciences Research Council (BBSRC, grant BB/M004856/1 to Andrew J. Flavell) and via the DFG priority program 1530: Flowering time control - from natural variation to crop improvement (grant Pi339/7-1 to Klaus Pillen). We thank Roswitha Ende, Jana Müglitz, Markus Hinz, Brigitte Schröder, Bernd Kollmorgen and various student assistants for excellent technical assistance at the Halle field station and Martin Bruce, Richard Keith Chris Warden and James Simpson for similar support in Dundee. The James Hutton Institute acknowledges the contribution of the Scottish Governments Rural Affairs and the Environment programme towards its funding.

PY - 2018/3/16

Y1 - 2018/3/16

N2 - Barley is cultivated more widely than the other major world crops because it adapts well to environmental constraints, such as drought, heat, and day length. To better understand the genetic control of local adaptation in barley, we studied development in the nested association mapping population HEB-25, derived from crossing 25 wild barley accessions with the cultivar 'Barke'. HEB-25 was cultivated in replicated field trials in Dundee (Scotland) and Halle (Germany), differing in regard to day length, precipitation, and temperature. Applying a genome-wide association study, we located 60 and 66 quantitative trait locus (QTL) regions regulating eight plant development traits in Dundee and Halle, respectively. A number of QTLs could be explained by known major genes such as PHOTOPERIOD 1 (Ppd-H1) and FLOWERING LOCUS T (HvFT-1) that regulate plant development. In addition, we observed that developmental traits in HEB-25 were partly controlled via genotype × environment and genotype × donor interactions, defined as location-specific and family-specific QTL effects. Our findings indicate that QTL alleles are available in the wild barley gene pool that show contrasting effects on plant development, which may be deployed to improve adaptation of cultivated barley to future environmental changes.

AB - Barley is cultivated more widely than the other major world crops because it adapts well to environmental constraints, such as drought, heat, and day length. To better understand the genetic control of local adaptation in barley, we studied development in the nested association mapping population HEB-25, derived from crossing 25 wild barley accessions with the cultivar 'Barke'. HEB-25 was cultivated in replicated field trials in Dundee (Scotland) and Halle (Germany), differing in regard to day length, precipitation, and temperature. Applying a genome-wide association study, we located 60 and 66 quantitative trait locus (QTL) regions regulating eight plant development traits in Dundee and Halle, respectively. A number of QTLs could be explained by known major genes such as PHOTOPERIOD 1 (Ppd-H1) and FLOWERING LOCUS T (HvFT-1) that regulate plant development. In addition, we observed that developmental traits in HEB-25 were partly controlled via genotype × environment and genotype × donor interactions, defined as location-specific and family-specific QTL effects. Our findings indicate that QTL alleles are available in the wild barley gene pool that show contrasting effects on plant development, which may be deployed to improve adaptation of cultivated barley to future environmental changes.

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KW - genome-wide association study (GWAS)

KW - genotype by donor interaction (GxD)

KW - genotype by environment interaction (GxE)

KW - nested association mapping (NAM)

KW - plant development

KW - quantitative trait locus (QTL)

KW - wild barley (Hordeum vulgare ssp. Spontaneum)

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DO - 10.1093/jxb/ery002

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SP - 1517

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JO - Journal of Experimental Botany

JF - Journal of Experimental Botany

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Contrasting genetic regulation of plant development in wild barley grown in two European environments revealed by nested association mapping

Abstract

Keywords

ASJC Scopus subject areas

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BARLEY_NAM - Locating Exotic Genes that Control Agronomic Traits Under Stress in the Wild Barley Nested Association Mapping (NAM) Population HEB-25 (ERA CAP Joint with Martin Luther University, Halle, The Hebrew University of Jerusalem, The Julius Kuhn Institute, Germany)

Cite this

Contrasting genetic regulation of plant development in wild barley grown in two European environments revealed by nested association mapping

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Projects

BARLEY_NAM - Locating Exotic Genes that Control Agronomic Traits Under Stress in the Wild Barley Nested Association Mapping (NAM) Population HEB-25 (ERA CAP Joint with Martin Luther University, Halle, The Hebrew University of Jerusalem, The Julius Kuhn Institute, Germany)

Cite this