Controversy in the link between Vitamin D supplementation and hypertension

Louise A. Beveridge, Miles D. Witham (Lead / Corresponding author)

    Research output: Contribution to journalArticle

    12 Citations (Scopus)

    Abstract

    Vitamin D affects a range of pathophysiological processes pertinent to the control of blood pressure, including endothelial function, inflammation and renin-angiotensin system activity. Observational data show a clear relationship between 25-hydroxyvitamin D levels and both current blood pressure and incident hypertension. However, recent trial data have shown no significant effect of vitamin D supplementation on blood pressure, even at high doses, low vitamin D levels and in patients with high baseline blood pressure. Vitamin D might still benefit cardiovascular health through mechanisms other than blood pressure reduction, but data from large trials are required to show this. In the meantime, vitamin D has no place in controlling blood pressure either at the individual or the population level.

    Original languageEnglish
    Pages (from-to)971-973
    Number of pages3
    JournalExpert Review of Cardiovascular Therapy
    Volume13
    Issue number9
    DOIs
    Publication statusPublished - 2015

    Keywords

    • Cardiovascular
    • Hypertension
    • Meta-analysis
    • Trials
    • Vitamin D

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