Could psoralen plus ultraviolet A1 ("PUVA1") work? Depth penetration achieved by phototherapy lamps

I R M Barnard (Lead / Corresponding author), E Eadie, L McMillan, H Moseley, T Brown, K Wood, R Dawe

Research output: Contribution to journalLetter


Psoralen and ultraviolet A (PUVA) is useful in treating various hand and foot skin diseases.1 Most cases of psoriasis respond well to phototherapy or PUVA. However, for some diseases, such as palmoplantar pustular psoriasis, PUVA is not always sufficient to produce therapeutic effect. If PUVA fails, it is sometimes necessary to progress to other treatments such as Grenz ray therapy (where available),2 systemic retinoid or systemic immunosuppression. Could "PUVA1" (psoralen combined with ultraviolet A1 long wavelength ultraviolet A [UVA]) work in cases where conventional PUVA (psoralen plus broadband UVA) has been inadequate?.

Original languageEnglish
Number of pages2
JournalBritish Journal of Dermatology
Publication statusE-pub ahead of print - 28 Sep 2019


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