Recently a novel mechanism has been described for the hydrophobic attachment of proteins to membranes, which is shared by membrane proteins of widely differing origin and function. The hydrophobic anchor is the 1,2-diacylglycerol moiety of a phosphatidylinositol molecule which is covalently attached to the polypeptide chain. These findings have important structural and functional implications.
Low, M. G., Ferguson, M. A. J., Futerman, A. H., & Silman, I. (1986). Covalently attached phosphatidylinositol as a hydrophobic anchor for membrane-proteins. Trends in Biochemical Sciences, 11(5), 212-215. https://doi.org/10.1016/0968-0004(86)90009-5