morbidities and mortalities in certain vulnerable populations. People Who Use Drugs (PWUD)
are a marginalized and stigmatized group with weaker immunity responses, vulnerability to
stress, poor health conditions, high-risk behaviors, and lower access to health care services.
These conditions put them at a higher risk of COVID-19 infection and its complications. In this
paper, an international group of experts on addiction medicine, infectious diseases, and disaster
psychiatry explore the possible raised concerns in this issue and provide recommendations to
manage the comorbidity of COVID-19 and Substance Use Disorder (SUD)