COVID and the Kidney: An Update

Samira Bell (Lead / Corresponding author), Griffith B. Perkins, Urmila Anandh, P. Toby Coates

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)
26 Downloads (Pure)

Abstract

Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, has led to a global pandemic that continues to be responsible for ongoing health issues for people worldwide. Immunocompromised individuals such as kidney transplant recipients and dialysis patients have been and continue to be among the most affected, with poorer outcomes after infection, impaired response to COVID-19 vaccines, and protracted infection. The pandemic also has had a significant impact on patients with underlying chronic kidney disease (CKD), with CKD increasing susceptibility to COVID-19, risk of hospital admission, and mortality. COVID-19 also has been shown to lead to acute kidney injury (AKI) through both direct and indirect mechanisms. The incidence of COVID-19 AKI has been decreasing as the pandemic has evolved, but continues to be associated with adverse patient outcomes correlating with the severity of AKI. There is also increasing evidence examining the longer-term effect of COVID-19 on the kidney demonstrating continued decline in kidney function several months after infection. This review summarizes the current evidence examining the impact of COVID-19 on the kidney, covering both the impact on patients with CKD, including patients receiving kidney replacement therapy, in addition to discussing COVID-19 AKI.
Original languageEnglish
Article number151471
Number of pages12
JournalSeminars in Nephrology
Volume43
Issue number5
DOIs
Publication statusE-pub ahead of print - 9 Jan 2024

Keywords

  • Acute kidney injury
  • COVID-19
  • chronic kidney disease
  • dialysis
  • transplant
  • vaccination

ASJC Scopus subject areas

  • Nephrology

Fingerprint

Dive into the research topics of 'COVID and the Kidney: An Update'. Together they form a unique fingerprint.

Cite this