Critical pH in resting and stimulated whole saliva in groups of children and adults

P. Anderson, M. P. Hector, M. A. Rampersad

    Research output: Contribution to journalArticlepeer-review

    86 Citations (Scopus)


    Objective. The concentrations of calcium and phosphate in saliva have significant influence on the protective mechanisms of dental hard tissues within the oral environment. A lower calcium concentration means: 1) a lower thermodynamic driving force for hydroxyapatite precipitation at normal oral pH; 2) a higher driving force for hydroxyapatite dissolution at low pH; 3) a lower critical pH. The aims of this study were to: 1. determine the calcium and phosphate concentrations 2. calculate the critical pH for enamel and 3. determine the driving forces for demineralization and remineralization in a group of children and adults. Methods. In this comparative study, calcium and phosphate concentrations were measured in the resting and stimulated saliva of child and adult volunteers using a spectrophotometric system used in routine blood analysis. Salivary flow rates were also measured in each group. Results. The calcium concentrations were lower in children than adults, but the phosphate concentrations were not significantly different. The critical pH was significantly higher for children than adults in both resting and stimulated saliva. Therefore, the thermodynamic driving forces for; (1) demineralisation at low oral pH, is greater, and (2) for remineralisation at normal oral pH, is lower, in children compared to adults. Conclusion. The results of this study show that from thermodynamic considerations alone, there is increased risk of demineralization in children compared with adults.

    Original languageEnglish
    Pages (from-to)266-273
    Number of pages8
    JournalInternational Journal of Paediatric Dentistry
    Issue number4
    Publication statusPublished - 1 Jul 2001

    ASJC Scopus subject areas

    • General Dentistry


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