TY - JOUR
T1 - CT morphometric analysis of thoracic vertebrae and pelvic parameters
T2 - implications for kyphosis and postural balance
AU - Karaca Bozdag, Zekiye
AU - Turkmen, Bilge
AU - Kilic Safak, Nazire
AU - Sonmez, Suleyman
AU - Oguz, Ozkan
AU - Soames, Roger W.
AU - Alashkham, Abduelmenem
N1 - Publisher Copyright:
© The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2025.
PY - 2025/12/10
Y1 - 2025/12/10
N2 - Objective: To investigate the relationship between thoracic vertebral morphometry and pelvic parameters, clarify their role in sagittal balance, and assess their predictive value for thoracic kyphosis and postural imbalance. Method: Thoracic CT images obtained between January/2002 and August/2025 were retrospectively reviewed, including 120 patients (60 with kyphosis, 60 controls). Variables comprised vertebral body and total vertebral volumes, spinous process morphometry, Cobb angle, pelvic incidence, sacral slope, pelvic tilt, and indices of pelvic symmetry, including distance and height differences between anterior superior iliac spines and femoral head centres. Statistical analyses included inter-group comparisons, correlations, logistic regression, and receiver operating characteristic evaluation. Results: The kyphosis group showed significantly greater pelvic incidence (58.9° vs. 50.9°), sacral slope (47.0° vs. 38.6°), and Cobb angle (47.9° vs. 29.2°) (all p < 0.01). Marked asymmetry was observed, with higher femoral head centre (13.0 mm vs. 1.6 mm) and anterior superior iliac spine height differences (12.9 mm vs. 2.0 mm) (p < 0.001). ROC analysis identified femoral head height difference > 5.1 mm (AUC = 0.812; sensitivity 80%, specificity 73%), anterior superior iliac spine height difference > 3.8 mm (AUC = 0.795), and sacral slope > 42.7° (AUC = 0.731) as reliable thresholds for predicting kyphosis. Pelvic incidence, sacral slope, Cobb angle, and asymmetry increased significantly in participants aged ≥ 60 years. Conclusion: Combined assessment of thoracic and pelvic morphometry showed that sagittal balance cannot be explained by angular measures alone. Simple indices such as femoral head and iliac spine height differences offer high predictive value for kyphosis and may guide as useful radiographic markers for identifying individuals at risk.
AB - Objective: To investigate the relationship between thoracic vertebral morphometry and pelvic parameters, clarify their role in sagittal balance, and assess their predictive value for thoracic kyphosis and postural imbalance. Method: Thoracic CT images obtained between January/2002 and August/2025 were retrospectively reviewed, including 120 patients (60 with kyphosis, 60 controls). Variables comprised vertebral body and total vertebral volumes, spinous process morphometry, Cobb angle, pelvic incidence, sacral slope, pelvic tilt, and indices of pelvic symmetry, including distance and height differences between anterior superior iliac spines and femoral head centres. Statistical analyses included inter-group comparisons, correlations, logistic regression, and receiver operating characteristic evaluation. Results: The kyphosis group showed significantly greater pelvic incidence (58.9° vs. 50.9°), sacral slope (47.0° vs. 38.6°), and Cobb angle (47.9° vs. 29.2°) (all p < 0.01). Marked asymmetry was observed, with higher femoral head centre (13.0 mm vs. 1.6 mm) and anterior superior iliac spine height differences (12.9 mm vs. 2.0 mm) (p < 0.001). ROC analysis identified femoral head height difference > 5.1 mm (AUC = 0.812; sensitivity 80%, specificity 73%), anterior superior iliac spine height difference > 3.8 mm (AUC = 0.795), and sacral slope > 42.7° (AUC = 0.731) as reliable thresholds for predicting kyphosis. Pelvic incidence, sacral slope, Cobb angle, and asymmetry increased significantly in participants aged ≥ 60 years. Conclusion: Combined assessment of thoracic and pelvic morphometry showed that sagittal balance cannot be explained by angular measures alone. Simple indices such as femoral head and iliac spine height differences offer high predictive value for kyphosis and may guide as useful radiographic markers for identifying individuals at risk.
KW - CT
KW - Kyphosis
KW - Morphometry of the thoracic vertebrae
KW - Pelvic parameters
KW - Postural stability
UR - https://www.scopus.com/pages/publications/105024686295
U2 - 10.1007/s00586-025-09652-9
DO - 10.1007/s00586-025-09652-9
M3 - Article
C2 - 41369753
AN - SCOPUS:105024686295
SN - 0940-6719
JO - European Spine Journal
JF - European Spine Journal
ER -