CTO pathophysiology: how does this affect management?

John Irving (Lead / Corresponding author)

    Research output: Contribution to journalArticle

    10 Citations (Scopus)

    Abstract

    Chronic total occlusion (CTO) pathophysiology has been described in a few, small studies using post mortem histology, and more recently, in vivo intravascular ultrasound (IVUS) to analyse the constituents of occluded segments. Recent improvements in equipment and techniques have revealed new insights into physical characteristics of occluded coronaries, which in turn enable predictable procedural success. The purpose of this review is to consider the published evidence describing CTO pathophysiology from the perspective of the hybrid algorithm approach to CTO PCI.
    Methods: Literature searches using "Chronic Occlusion", "angioplasty", and" pathology" as keywords. Further searches on "coronary" "collateral", "Viability". Bibliographies were scrutinised for further key publications in an iterative process. Papers describing animal models were excluded.
    Original languageEnglish
    Pages (from-to)99-107
    Number of pages9
    JournalCurrent Cardiology Reviews
    Volume10
    Issue number2
    DOIs
    Publication statusPublished - 2014

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