Dark chocolate inhibits platelet aggregation in healthy volunteers

Andrew J. Innes, Gwen Kennedy, Margaret McLaren, Anne J. Bancroft, Jill J. F. Belch

    Research output: Contribution to journalArticle

    76 Citations (Scopus)

    Abstract

    Cardiovascular disease is a leading cause of death in the UK. The flavonoids found in cocoa may produce a cardio-protective role for chocolate with a high cocoa content. Thirty healthy volunteers were randomised to receive 100 g of white, milk or dark chocolate, and assessments of platelet function were undertaken on venous blood samples before and after chocolate consumption. White and milk chocolate had no significant effect on platelets. However dark chocolate inhibited collagen-induced platelet aggregation in platelet rich plasma. In the future dark chocolate may have a role in prevention of cardiovascular and thromboembolic diseases.
    Original languageEnglish
    Pages (from-to)325-327
    Number of pages3
    JournalPlatelets
    Volume14
    Issue number5
    Publication statusPublished - Aug 2003

    Fingerprint

    Platelet Aggregation
    Healthy Volunteers
    Milk
    Cardiovascular Diseases
    Blood Platelets
    Platelet-Rich Plasma
    Flavonoids
    Chocolate
    Cause of Death
    Collagen

    Cite this

    Innes, Andrew J. ; Kennedy, Gwen ; McLaren, Margaret ; Bancroft, Anne J. ; Belch, Jill J. F. / Dark chocolate inhibits platelet aggregation in healthy volunteers. In: Platelets. 2003 ; Vol. 14, No. 5. pp. 325-327.
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    abstract = "Cardiovascular disease is a leading cause of death in the UK. The flavonoids found in cocoa may produce a cardio-protective role for chocolate with a high cocoa content. Thirty healthy volunteers were randomised to receive 100 g of white, milk or dark chocolate, and assessments of platelet function were undertaken on venous blood samples before and after chocolate consumption. White and milk chocolate had no significant effect on platelets. However dark chocolate inhibited collagen-induced platelet aggregation in platelet rich plasma. In the future dark chocolate may have a role in prevention of cardiovascular and thromboembolic diseases.",
    author = "Innes, {Andrew J.} and Gwen Kennedy and Margaret McLaren and Bancroft, {Anne J.} and Belch, {Jill J. F.}",
    year = "2003",
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    Innes, AJ, Kennedy, G, McLaren, M, Bancroft, AJ & Belch, JJF 2003, 'Dark chocolate inhibits platelet aggregation in healthy volunteers', Platelets, vol. 14, no. 5, pp. 325-327.

    Dark chocolate inhibits platelet aggregation in healthy volunteers. / Innes, Andrew J.; Kennedy, Gwen; McLaren, Margaret; Bancroft, Anne J.; Belch, Jill J. F.

    In: Platelets, Vol. 14, No. 5, 08.2003, p. 325-327.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Dark chocolate inhibits platelet aggregation in healthy volunteers

    AU - Innes, Andrew J.

    AU - Kennedy, Gwen

    AU - McLaren, Margaret

    AU - Bancroft, Anne J.

    AU - Belch, Jill J. F.

    PY - 2003/8

    Y1 - 2003/8

    N2 - Cardiovascular disease is a leading cause of death in the UK. The flavonoids found in cocoa may produce a cardio-protective role for chocolate with a high cocoa content. Thirty healthy volunteers were randomised to receive 100 g of white, milk or dark chocolate, and assessments of platelet function were undertaken on venous blood samples before and after chocolate consumption. White and milk chocolate had no significant effect on platelets. However dark chocolate inhibited collagen-induced platelet aggregation in platelet rich plasma. In the future dark chocolate may have a role in prevention of cardiovascular and thromboembolic diseases.

    AB - Cardiovascular disease is a leading cause of death in the UK. The flavonoids found in cocoa may produce a cardio-protective role for chocolate with a high cocoa content. Thirty healthy volunteers were randomised to receive 100 g of white, milk or dark chocolate, and assessments of platelet function were undertaken on venous blood samples before and after chocolate consumption. White and milk chocolate had no significant effect on platelets. However dark chocolate inhibited collagen-induced platelet aggregation in platelet rich plasma. In the future dark chocolate may have a role in prevention of cardiovascular and thromboembolic diseases.

    M3 - Article

    VL - 14

    SP - 325

    EP - 327

    JO - Platelets

    JF - Platelets

    SN - 0953-7104

    IS - 5

    ER -