Dark chocolate inhibits platelet aggregation in healthy volunteers

TY - JOUR

T1 - Dark chocolate inhibits platelet aggregation in healthy volunteers

AU - Innes, Andrew J.

AU - Kennedy, Gwen

AU - McLaren, Margaret

AU - Bancroft, Anne J.

AU - Belch, Jill J. F.

PY - 2003/8

Y1 - 2003/8

N2 - Cardiovascular disease is a leading cause of death in the UK. The flavonoids found in cocoa may produce a cardio-protective role for chocolate with a high cocoa content. Thirty healthy volunteers were randomised to receive 100 g of white, milk or dark chocolate, and assessments of platelet function were undertaken on venous blood samples before and after chocolate consumption. White and milk chocolate had no significant effect on platelets. However dark chocolate inhibited collagen-induced platelet aggregation in platelet rich plasma. In the future dark chocolate may have a role in prevention of cardiovascular and thromboembolic diseases.

AB - Cardiovascular disease is a leading cause of death in the UK. The flavonoids found in cocoa may produce a cardio-protective role for chocolate with a high cocoa content. Thirty healthy volunteers were randomised to receive 100 g of white, milk or dark chocolate, and assessments of platelet function were undertaken on venous blood samples before and after chocolate consumption. White and milk chocolate had no significant effect on platelets. However dark chocolate inhibited collagen-induced platelet aggregation in platelet rich plasma. In the future dark chocolate may have a role in prevention of cardiovascular and thromboembolic diseases.

M3 - Article

C2 - 12944249

SN - 0953-7104

VL - 14

SP - 325

EP - 327

JO - Platelets

JF - Platelets

IS - 5

ER -