@article{8af2798796994bedad73b231f0401c16,
title = "Data management challenges in three-dimensional EM",
abstract = "This report describes the outcomes of the Data Management Challenges in 3D Electron Microscopy workshop. Key topics discussed include data models, validation and raw-data archiving. The meeting participants agreed that the EMDataBank should take the lead in addressing these issues, and concrete action points were agreed upon that will have a substantial impact on the accessibility of three-dimensional EM data in biology and medicine.",
author = "Ardan Patwardhan and Carazo, \{Jos{\'e} Maria\} and Bridget Carragher and Richard Henderson and Heymann, \{J. Bernard\} and Emma Hill and Jensen, \{Grant J.\} and Ingvar Lagerstedt and Lawson, \{Catherine L.\} and Ludtke, \{Steven J.\} and David Mastronarde and Moore, \{William J.\} and Alan Roseman and Peter Rosenthal and Sorzano, \{Carlos Oscar S.\} and Eduardo Sanz-Garc{\'i}a and Scheres, \{Sjors H.W.\} and Sriram Subramaniam and John Westbrook and Martyn Winn and Swedlow, \{Jason R.\} and Kleywegt, \{Gerard J.\}",
note = "Funding Information: for Electron Cryo-microscopy (CCP-EM), and outlined experiences gained with CCP4 and possible synergies with CCP-EM. Three participants from the University of Dundee represented the OME team, which develops scientific image-file-translation libraries and data-management applications12,13. PDBe and OME work together to apply OME resources to 3DEM data in the EMDB, and the workshop was sponsored by a joint Biotechnology and Biological Sciences Research Council (BBSRC) grant that stimulates collaboration between groups with expertise in handling 3DEM and light-microscopy data. Finally, six participants represented the EMDataBank. Funding Information: We thank P. Haslam for help with the manuscript. This workshop and the OMERO-EMDB project are supported by the BBSRC (BB/G022577). The EMDataBank is funded by the US National Institutes of Health National Institute of General Medical Sciences (R01GM079429). The work on the EMDB at the PDBe also profits from funding by European Molecular Biology Laboratory–EBI and the Wellcome Trust (088944).",
year = "2012",
month = dec,
day = "5",
doi = "10.1038/nsmb.2426",
language = "English",
volume = "19",
pages = "1203--1207",
journal = "Nature Structural and Molecular Biology",
issn = "1545-9993",
publisher = "Nature Research",
number = "12",
}