Deep tissue contractility sensing with biointegrated microlasers

Marcel Schubert (Lead / Corresponding author), Lewis Woolfson, Isla R.M. Barnard, Amy M. Dorward, Becky Casement, Soraya Caixeiro, Andrew Morton, Gavin B. Robertson, Paul L. Appleton, Gareth B. Miles, Carl S. Tucker, Samantha J. Pitt, Malte C. Gather

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Characterizing single cell contractility in the beating heart is strongly limited by light scattering and extreme tissue dynamics. Here, we use tissue-integrated microlasers to measure contractility in live zebrafish and living myocardial slices at a depth several times deeper than multiphoton microscopy-based techniques.

Original languageEnglish
Title of host publicationNovel Techniques in Microscopy, NTM 2021
PublisherThe Optical Society
ISBN (Electronic)9781557528209
Publication statusPublished - Apr 2021
EventNovel Techniques in Microscopy, NTM 2021 - Part of Biophotonics Congress: Optics in the Life Sciences 2021 - Virtual, Online, United States
Duration: 12 Apr 202116 Apr 2021

Publication series

NameOptics InfoBase Conference Papers

Conference

ConferenceNovel Techniques in Microscopy, NTM 2021 - Part of Biophotonics Congress: Optics in the Life Sciences 2021
Country/TerritoryUnited States
CityVirtual, Online
Period12/04/2116/04/21

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